Abstract Background Lipid droplet (LD) formation and size regulation reflects both lipid influx and efflux, and is central in the regulation of adipocyte metabolism, including adipokine secretion. The length and degree of dietary fatty acid (FA) unsaturation is implicated in LD formation and regulation in adipocytes. The aims of this study were to establish the impact of eicosapentaenoic acid (EPA; C20:5n-3) in comparison to SFA (STA; stearic acid, C18:0) and MUFA (OLA; oleic acid, C18:1n-9) on 3T3-L1 adipocyte LD formation, regulation of genes central to LD function and adipokine responsiveness. Cells were supplemented with 100 μM FA during 7-day differentiation. Results EPA markedly reduced LD size and total lipid accumulation, suppressin...
Dietary fatty acids, in particular long-chain fatty acids (LCFA), are involved in the regulation of ...
Many studies indicate that hyperlipidemia is associated with obesity and type 2 diabetes mellitus de...
International audienceVisfatin is an adipokine highly expressed in visceral adipose tissue (AT) of h...
Background : Lipid droplet (LD) formation and size regulation reflects both lipid influx and efflux,...
The comparative studies of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) effects on the...
Background: The effects of long-chain n-3 and n-6 polyunsaturated fatty acids (PUFA) on the regulati...
Background: Obesity is associated with an overexpansion of adipose tissue, along with increases in b...
Adipose tissue and its hormones have an irreplaceable role in the physiology of mammals. The imbalan...
International audienceMetabolic disorders related to obesity are largely dependent on adipose tissue...
Eicosapentaenoic acid (EPA), one of the n-3 polyunsaturated fatty acids, has been shown to stimulate...
Adipose tissue function is key determinant of metabolic health, with specific nutrients being sugges...
Obesity is an excess of adipose tissue and is linked with increased inflammation that enhances risk ...
The intake of v-3 polyunsaturated fatty acids (PUFAs), which are abundant in marine fish meat and oi...
Abstract Background Enhancing circulating adiponectin is considered as a potential approach for the ...
Abstract Background Increased consumption of omega-3 (ω-3) fatty acids found in cold-water fish and ...
Dietary fatty acids, in particular long-chain fatty acids (LCFA), are involved in the regulation of ...
Many studies indicate that hyperlipidemia is associated with obesity and type 2 diabetes mellitus de...
International audienceVisfatin is an adipokine highly expressed in visceral adipose tissue (AT) of h...
Background : Lipid droplet (LD) formation and size regulation reflects both lipid influx and efflux,...
The comparative studies of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) effects on the...
Background: The effects of long-chain n-3 and n-6 polyunsaturated fatty acids (PUFA) on the regulati...
Background: Obesity is associated with an overexpansion of adipose tissue, along with increases in b...
Adipose tissue and its hormones have an irreplaceable role in the physiology of mammals. The imbalan...
International audienceMetabolic disorders related to obesity are largely dependent on adipose tissue...
Eicosapentaenoic acid (EPA), one of the n-3 polyunsaturated fatty acids, has been shown to stimulate...
Adipose tissue function is key determinant of metabolic health, with specific nutrients being sugges...
Obesity is an excess of adipose tissue and is linked with increased inflammation that enhances risk ...
The intake of v-3 polyunsaturated fatty acids (PUFAs), which are abundant in marine fish meat and oi...
Abstract Background Enhancing circulating adiponectin is considered as a potential approach for the ...
Abstract Background Increased consumption of omega-3 (ω-3) fatty acids found in cold-water fish and ...
Dietary fatty acids, in particular long-chain fatty acids (LCFA), are involved in the regulation of ...
Many studies indicate that hyperlipidemia is associated with obesity and type 2 diabetes mellitus de...
International audienceVisfatin is an adipokine highly expressed in visceral adipose tissue (AT) of h...