Recently reconstructing evolutionary histories has become a computational issue due to the increased availability of genetic sequencing data and relaxations of classical modelling assumptions. This thesis specializes a Divide & conquer sequential Monte Carlo (DCSMC) inference algorithm to phylogenetics to address these challenges. In phylogenetics, the tree structure used to represent evolutionary histories provides a model decomposition used for DCSMC. In particular, speciation events are used to recursively decompose the model into subproblems. Each subproblem is approximated by an independent population of weighted particles, which are merged and propagated to create an ancestral population. This approach provides the flexibility to rela...
Talk given at Evolution 2016 in the SSB Spotlight: Next generation phylogenetic inference 1. Evolu...
Phylogenetic stochastic mapping is a method for reconstructing the history of trait changes on a phy...
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Compute...
Recently reconstructing evolutionary histories has become a computational issue due to the increased...
A main task in evolutionary biology is phylogenetic tree reconstruction, which determines the ancest...
Abstract.—Bayesian inference provides an appealing general framework for phylogenetic analysis, able...
Bayesian inference provides an appealing general framework for phylogenetic analysis, able to incorp...
The application of Bayesian methods to large scale phylogenetics problems is increasingly limited by...
Monte Carlo methods have emerged as standard tools to do Bayesian statistical inference for sophisti...
This article is organized as follows: Section 2 opens with an introduction to the requisite terminol...
Bayesian phylogenetics, which approximates a posterior distribution of phylogenetic trees, has becom...
We observe n sequences at each of m sites, and assume that they have evolved from an ancestral seque...
The multispecies coalescent (MSC) is a statistical framework that models how gene genealogies grow w...
Modern infectious disease outbreak surveillance produces continuous streams of sequence data which r...
The multispecies coalescent (MSC) is a statistical framework that models how gene genealogies grow w...
Talk given at Evolution 2016 in the SSB Spotlight: Next generation phylogenetic inference 1. Evolu...
Phylogenetic stochastic mapping is a method for reconstructing the history of trait changes on a phy...
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Compute...
Recently reconstructing evolutionary histories has become a computational issue due to the increased...
A main task in evolutionary biology is phylogenetic tree reconstruction, which determines the ancest...
Abstract.—Bayesian inference provides an appealing general framework for phylogenetic analysis, able...
Bayesian inference provides an appealing general framework for phylogenetic analysis, able to incorp...
The application of Bayesian methods to large scale phylogenetics problems is increasingly limited by...
Monte Carlo methods have emerged as standard tools to do Bayesian statistical inference for sophisti...
This article is organized as follows: Section 2 opens with an introduction to the requisite terminol...
Bayesian phylogenetics, which approximates a posterior distribution of phylogenetic trees, has becom...
We observe n sequences at each of m sites, and assume that they have evolved from an ancestral seque...
The multispecies coalescent (MSC) is a statistical framework that models how gene genealogies grow w...
Modern infectious disease outbreak surveillance produces continuous streams of sequence data which r...
The multispecies coalescent (MSC) is a statistical framework that models how gene genealogies grow w...
Talk given at Evolution 2016 in the SSB Spotlight: Next generation phylogenetic inference 1. Evolu...
Phylogenetic stochastic mapping is a method for reconstructing the history of trait changes on a phy...
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Compute...