Each year about 1.5 million people die from lung cancer worldwide. In order to develop more effective strategies to manage this disease, it is essential to have a better understanding of molecular mechanisms underlying lung tumourigenesis. A recognized fact about cancer in general is that it shares many biological similarities with normal fetal development, such as intense cell proliferation, migration, angiogenesis and immune evasion. These features are gained as a consequence of changes in gene expression, which can result from the disruption in miRNAs. This class of small non-coding RNAs plays a fundamental role in regulating gene expression during normal development and tumourigenesis, nevertheless, comprehensive analyses of miRNAs in...
Background: It has been demonstrated that, at the network level, the transcriptional regulation by ...
Background: Few genetic markers useful for the screening of lung cancer risk exist. Although related...
Lung cancer remains the most lethal cancer among men and women in the United States and worldwide. T...
Late diagnosis and resistance to targeted therapies are significant obstacles to improving cancer pa...
Abstract:Lung cancer is the leading cause of cancer related deaths in the United States. It is estim...
MicroRNA (miRNAs) is a group of small non-coding RNAs. It is involved in multiple cellular processes...
MicroRNAs (miRNAs) play vital roles in the regulation of normal developmental pathways. However, can...
Lung cancer genomic profiling has led to the development of therapies targeting aberrant protein exp...
Lung cancer genomic profiling has led to the development of therapies targeting aberrant protein exp...
Lung cancers account for a huge percentage of death in industrialized countries, and hence there is ...
Purpose: The molecular drivers that determine histology in lung cancer are largely unknown. We inves...
Abstract Carcinoma of the lung is among the most common types of cancer globally. Concerning its his...
While previous studies reported aberrant expression of microRNAs (miRNAs) in non-small cell lung can...
Lung cancer is the first cause of cancer death in the world due to its high prevalence, aggressivene...
Lung carcinoma is the leading cause of cancer-related death worldwide; it has been regarded as the o...
Background: It has been demonstrated that, at the network level, the transcriptional regulation by ...
Background: Few genetic markers useful for the screening of lung cancer risk exist. Although related...
Lung cancer remains the most lethal cancer among men and women in the United States and worldwide. T...
Late diagnosis and resistance to targeted therapies are significant obstacles to improving cancer pa...
Abstract:Lung cancer is the leading cause of cancer related deaths in the United States. It is estim...
MicroRNA (miRNAs) is a group of small non-coding RNAs. It is involved in multiple cellular processes...
MicroRNAs (miRNAs) play vital roles in the regulation of normal developmental pathways. However, can...
Lung cancer genomic profiling has led to the development of therapies targeting aberrant protein exp...
Lung cancer genomic profiling has led to the development of therapies targeting aberrant protein exp...
Lung cancers account for a huge percentage of death in industrialized countries, and hence there is ...
Purpose: The molecular drivers that determine histology in lung cancer are largely unknown. We inves...
Abstract Carcinoma of the lung is among the most common types of cancer globally. Concerning its his...
While previous studies reported aberrant expression of microRNAs (miRNAs) in non-small cell lung can...
Lung cancer is the first cause of cancer death in the world due to its high prevalence, aggressivene...
Lung carcinoma is the leading cause of cancer-related death worldwide; it has been regarded as the o...
Background: It has been demonstrated that, at the network level, the transcriptional regulation by ...
Background: Few genetic markers useful for the screening of lung cancer risk exist. Although related...
Lung cancer remains the most lethal cancer among men and women in the United States and worldwide. T...