Pim-1 is an oncogene-encoded serine-threonine kinase, expressed primarily in hematopoietic and germ cells. Previously identified only in mammalian systems, pim-1 was cloned and sequenced from Xenopus laevis, the African clawed frog. The coding region of X. laevis Pim-1 encoded a protein of 324 amino acids, which exhibited 64% amino acid sequence identity with the full-length human protein. PCR was also used to demonstrate the existence of Pim-1 in Pisaster ochraceus, the purple sea star. The high sequence conservation observed in the catalytic domain of Pim-1 between divergent species support a conserved and important function for this kinase. The full-length coding regions of both human and X. laevis Pim-1 were expressed as recomb...
Background: Pim-1 is a serine-threonine kinase which promotes early transformation, cell proliferati...
PIM1, a serine/threonine protein kinase, is a stress-induced kinase regulated by cytokines, growth f...
The Pim proteins are a family of highly homologous protein serine/threonine kinases that have been f...
Pim-1 is an oncogene-encoded serine-threonine kinase, expressed primarily in hematopoietic and germ...
The protein PIM-1 is a serine/threonine kinase which is expressed of the gene pim-1. pim-1 is a prot...
The Pim kinases are a family of three vertebrate protein serine/threonine kinases (Pim-1, -2, and -3...
We have cloned a novel quail cDNA with strong homology to the pint family of proto-oncogenes. The de...
Pim-1 kinase belongs to the family of serine/threonine protein kinases (EC 2.7.11.1) encoded by the ...
The Pim kinases are a family of three vertebrate protein serine/threonine kinases (Pim-1, -2, and -3...
The PIM proteins, which were initially discovered as proviral insertion sites in Moloney murine leuk...
The PIM family of serine/threonine kinases has three highly conserved isoforms (PIM1, PIM2 and PIM3)...
The proviral insertion site in Moloney murine leukemia virus, or PIM proteins, are a family of serin...
The PIM family of serine/threonine kinases has three highly conserved isoforms (PIM1, PIM2 and PIM3)...
Protein kinases constitute one of the largest and most pleiotropic families of proteins. Mutations ...
<div><p>Pim-1 kinase, a serine/threonine protein kinase encoded by the <i>pim</i> proto-oncogene, is...
Background: Pim-1 is a serine-threonine kinase which promotes early transformation, cell proliferati...
PIM1, a serine/threonine protein kinase, is a stress-induced kinase regulated by cytokines, growth f...
The Pim proteins are a family of highly homologous protein serine/threonine kinases that have been f...
Pim-1 is an oncogene-encoded serine-threonine kinase, expressed primarily in hematopoietic and germ...
The protein PIM-1 is a serine/threonine kinase which is expressed of the gene pim-1. pim-1 is a prot...
The Pim kinases are a family of three vertebrate protein serine/threonine kinases (Pim-1, -2, and -3...
We have cloned a novel quail cDNA with strong homology to the pint family of proto-oncogenes. The de...
Pim-1 kinase belongs to the family of serine/threonine protein kinases (EC 2.7.11.1) encoded by the ...
The Pim kinases are a family of three vertebrate protein serine/threonine kinases (Pim-1, -2, and -3...
The PIM proteins, which were initially discovered as proviral insertion sites in Moloney murine leuk...
The PIM family of serine/threonine kinases has three highly conserved isoforms (PIM1, PIM2 and PIM3)...
The proviral insertion site in Moloney murine leukemia virus, or PIM proteins, are a family of serin...
The PIM family of serine/threonine kinases has three highly conserved isoforms (PIM1, PIM2 and PIM3)...
Protein kinases constitute one of the largest and most pleiotropic families of proteins. Mutations ...
<div><p>Pim-1 kinase, a serine/threonine protein kinase encoded by the <i>pim</i> proto-oncogene, is...
Background: Pim-1 is a serine-threonine kinase which promotes early transformation, cell proliferati...
PIM1, a serine/threonine protein kinase, is a stress-induced kinase regulated by cytokines, growth f...
The Pim proteins are a family of highly homologous protein serine/threonine kinases that have been f...