Abstract Background Gene expression microarray experiments are expensive to conduct and guidelines for acceptable quality control at intermediate steps before and after the samples are hybridised to chips are vague. We conducted an experiment hybridising RNA from human brain to 117 U133A Affymetrix GeneChips and used these data to explore the relationship between 4 pre-chip variables and 22 post-chip outcomes and quality control measures. Results We found that the pre-chip variables were significantly correlated with each other but that this correlation was strongest between measures of RNA quality and cRNA yield. Post-mortem interval was negatively correlated with these variables. Four principal components, reflecting array outliers, array...
<p>Analysis of array data of all 75 samples run was carried out in Affymetrix Expression Console. Po...
Affymetrix GeneChips are one of the best established microarray platforms. This powerful technique a...
Affymetrix GeneChips are one of the best established microarray platforms. This powerful technique a...
Background Gene expression microarray experiments are expensive to conduct and guidelines for accept...
Background: Gene expression microarray experiments are expensive to conduct and guidelines for accep...
Background: Gene expression microarray experiments are expensive to conduct and guidelines for accep...
Background: Gene expression microarray experiments are expensive to conduct and guidelines for accep...
Background: Gene expression microarray experiments are expensive to conduct and guidelines for accep...
DNA microarray technology enables investigators to measure the expression of several 1000 mRNA speci...
DNA microarray technology enables investigators to measure the expression of several 1000 mRNA speci...
DNA microarray technology enables investigators to measure the expression of several 1000 mRNA speci...
Abstract Background Large-scale gene expression analysis of post-mortem brain tissue offers unique o...
Abstract Background Microarray technology has become a widely used tool in the biological sciences. ...
Abstract Background The maturing of gene expression microarray technology and interest in the use of...
Quality of microarray gene expression data has emerged as a new research topic. As in other areas, m...
<p>Analysis of array data of all 75 samples run was carried out in Affymetrix Expression Console. Po...
Affymetrix GeneChips are one of the best established microarray platforms. This powerful technique a...
Affymetrix GeneChips are one of the best established microarray platforms. This powerful technique a...
Background Gene expression microarray experiments are expensive to conduct and guidelines for accept...
Background: Gene expression microarray experiments are expensive to conduct and guidelines for accep...
Background: Gene expression microarray experiments are expensive to conduct and guidelines for accep...
Background: Gene expression microarray experiments are expensive to conduct and guidelines for accep...
Background: Gene expression microarray experiments are expensive to conduct and guidelines for accep...
DNA microarray technology enables investigators to measure the expression of several 1000 mRNA speci...
DNA microarray technology enables investigators to measure the expression of several 1000 mRNA speci...
DNA microarray technology enables investigators to measure the expression of several 1000 mRNA speci...
Abstract Background Large-scale gene expression analysis of post-mortem brain tissue offers unique o...
Abstract Background Microarray technology has become a widely used tool in the biological sciences. ...
Abstract Background The maturing of gene expression microarray technology and interest in the use of...
Quality of microarray gene expression data has emerged as a new research topic. As in other areas, m...
<p>Analysis of array data of all 75 samples run was carried out in Affymetrix Expression Console. Po...
Affymetrix GeneChips are one of the best established microarray platforms. This powerful technique a...
Affymetrix GeneChips are one of the best established microarray platforms. This powerful technique a...