Virtual screening (VS) methods have emerged as an adaptive response to massive throughput synthesis and screening technologies. Based on the structure-permeability paradigm, the Lipinski rule of five has become a standard property filtering protocol for VS. Three possible VS scenarios with respect to optimising binding affinity and pharmacokinetic properties are discussed. The parsimony principle for selecting candidate leads for further optimisation is advocated
At the onset of a drug discovery program, the goal is to identify novel compounds with appropriate c...
Virtual screening (VS) overcomes the limitations of traditional high-throughput screening (HTS) by a...
Importance of the field: Virtual screening is a computer-based technique for identifying promising c...
Virtual screening (VS) methods have emerged as an adaptive response to massive throughput synthesis ...
Drug discovery continues to be one of the greatest contemporary challenges and rational application ...
Virtual screening emerged as an important tool in our quest to access novel drug like compounds. The...
Virtual screening (VS) is a powerful technique for identifying hit molecules as starting points for ...
Virtual screening (VS) is a powerful technique for identifying hit molecules as starting points for ...
Virtual screening (VS) is a powerful technique for identifying hit molecules as starting points for ...
Virtual screening, especially the structure-based virtual screening, has emerged as a reliable, cost...
Abstract: Virtual screening, especially the structure-based virtual screening, has emerged as a reli...
There are several methods for virtual screening of databases of small organic compounds to find tigh...
Virtual screening represents an effective computational strategy to rise-up the chances of finding n...
Virtual screening consists of using computational tools to predict potentially bioactive compounds f...
The aim of virtual high-throughput screening is the identification of biologically relevant molecule...
At the onset of a drug discovery program, the goal is to identify novel compounds with appropriate c...
Virtual screening (VS) overcomes the limitations of traditional high-throughput screening (HTS) by a...
Importance of the field: Virtual screening is a computer-based technique for identifying promising c...
Virtual screening (VS) methods have emerged as an adaptive response to massive throughput synthesis ...
Drug discovery continues to be one of the greatest contemporary challenges and rational application ...
Virtual screening emerged as an important tool in our quest to access novel drug like compounds. The...
Virtual screening (VS) is a powerful technique for identifying hit molecules as starting points for ...
Virtual screening (VS) is a powerful technique for identifying hit molecules as starting points for ...
Virtual screening (VS) is a powerful technique for identifying hit molecules as starting points for ...
Virtual screening, especially the structure-based virtual screening, has emerged as a reliable, cost...
Abstract: Virtual screening, especially the structure-based virtual screening, has emerged as a reli...
There are several methods for virtual screening of databases of small organic compounds to find tigh...
Virtual screening represents an effective computational strategy to rise-up the chances of finding n...
Virtual screening consists of using computational tools to predict potentially bioactive compounds f...
The aim of virtual high-throughput screening is the identification of biologically relevant molecule...
At the onset of a drug discovery program, the goal is to identify novel compounds with appropriate c...
Virtual screening (VS) overcomes the limitations of traditional high-throughput screening (HTS) by a...
Importance of the field: Virtual screening is a computer-based technique for identifying promising c...
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