Abstract Confocal Raman microscopy as a label-free technique was applied to study the uptake and internalization of poly(lactide-co-glycolide) (PLGA) nanoparticles (NPs) and carbon nanotubes (CNTs) into hepatocarcinoma human HepG2 cells. Spontaneous confocal Raman spectra was recorded from the cells exposed to oxidized CNTs and to PLGA NPs. The Raman spectra showed bands arising from the cellular environment: lipids, proteins, nucleic acids, as well as bands characteristic for either PLGA NPs or CNTs. The simultaneous generation of Raman bands from the cell and nanomaterials from the same spot proves internalization, and also indicates the cellular region, where the nanomaterial is located. For PLGA NPs, it was found that they preferentiall...
AbstractNonresonant confocal Raman imaging has been used to map the DNA and the protein distribution...
The internalization kinetics and intracellular spatial distribution of functionalized diatomite nano...
Raman microscopy is employed to spectroscopically image biological cells previously exposed to fluor...
Confocal Raman Microscopy, a non-invasive, non-destructive and label-free technique, was employed to...
Carbon nanotube uptake was measured via high-speed confocal Raman imaging in live cells. Spatial and...
In this work, we employed the Raman microscopy to study the internalization kinetics and spatial dis...
Recently portable Raman probes have emerged along with a variety of applications, including carbon n...
Porous biosilica nanoparticles obtained from diatomites (DNPs) have been recently demonstrated to be...
Ease of sample preparation, narrow spectral bandwidth and minimal influence from water are features ...
International audienceUsing stem cells as anticancer drug carriers aims for targeting tumors and red...
Current methods for the evaluation of cellular interactions with nanoparticles are non-specific, rel...
Laponite is a nanoplatform that has been successfully used as a new biomaterial for drug delivery, t...
Abstract: Recent developments in combining Raman spectroscopy with optical microscopy provide a new ...
Progress in advanced therapeutic concepts requires the development of appropriate carrier systems fo...
Nonresonant confocal Raman imaging has been used to map the DNA and the protein distributions in ind...
AbstractNonresonant confocal Raman imaging has been used to map the DNA and the protein distribution...
The internalization kinetics and intracellular spatial distribution of functionalized diatomite nano...
Raman microscopy is employed to spectroscopically image biological cells previously exposed to fluor...
Confocal Raman Microscopy, a non-invasive, non-destructive and label-free technique, was employed to...
Carbon nanotube uptake was measured via high-speed confocal Raman imaging in live cells. Spatial and...
In this work, we employed the Raman microscopy to study the internalization kinetics and spatial dis...
Recently portable Raman probes have emerged along with a variety of applications, including carbon n...
Porous biosilica nanoparticles obtained from diatomites (DNPs) have been recently demonstrated to be...
Ease of sample preparation, narrow spectral bandwidth and minimal influence from water are features ...
International audienceUsing stem cells as anticancer drug carriers aims for targeting tumors and red...
Current methods for the evaluation of cellular interactions with nanoparticles are non-specific, rel...
Laponite is a nanoplatform that has been successfully used as a new biomaterial for drug delivery, t...
Abstract: Recent developments in combining Raman spectroscopy with optical microscopy provide a new ...
Progress in advanced therapeutic concepts requires the development of appropriate carrier systems fo...
Nonresonant confocal Raman imaging has been used to map the DNA and the protein distributions in ind...
AbstractNonresonant confocal Raman imaging has been used to map the DNA and the protein distribution...
The internalization kinetics and intracellular spatial distribution of functionalized diatomite nano...
Raman microscopy is employed to spectroscopically image biological cells previously exposed to fluor...