Abstract Background Down syndrome (DS) is the most common and best-known chromosomal disorder and is associated with several other pathologic conditions including immunodeficiency which makes a significant contribution to morbidity and mortality. Various immunological theories and observations to explain the predisposition of individuals with DS to various infections have been published, one of which is increased apoptotic cells. Aim The aim of this study was to identify the effect of apoptosis on both types of cells of specific immune response (T and B lymphocytes) in children with DS using Annexin V staining of phosphatidyserine (PS) as a specific marker of early apoptosis. Subjects and methods The study included 17 children with karyotyp...
Children with Down syndrome (DS) have increased susceptibility to infections and a high frequency of...
Individuals with Down syndrome (DS) have a high incidence of immunological alterations with increase...
Individuals with Down syndrome (DS) have a high incidence of immunological alterations with increase...
Down syndrome (DS) resembles immunodeficiency with increased infections, auto-immune diseases, and h...
Background: Down's syndrome (DS) patients present a high risk of developing alterations of the immun...
Immune defects, thyroid abnormalities, infections and coeliac disease are often associated with Down...
Individuals with Down syndrome (US) suffer from increased incidence of respiratory infections and ly...
PubMedID: 20477881The objective of this study was to evaluate the relationship between humoral and c...
Down syndrome (DS), the most common chromosomal abnormality in humans, is characterized by precociou...
Down syndrome (DS) is associated with increased susceptibility to infections, auto-immunity, immunod...
AbstractDifferent types of cells from subjects with Down syndrome (DS) have an increased susceptibil...
Phenotype and proliferative ability of peripheral blood lymphocytes from 15 noninstitutionalized chi...
Different types of cells from subjects with Down syndrome (DS) have an increased susceptibility to c...
Phenotype and proliferative ability of peripheral blood lymphocytes from 15 noninstitutionalized chi...
AbstractIt is hypothesized that Down syndrome (DS) patients are associated with abnormalities of the...
Children with Down syndrome (DS) have increased susceptibility to infections and a high frequency of...
Individuals with Down syndrome (DS) have a high incidence of immunological alterations with increase...
Individuals with Down syndrome (DS) have a high incidence of immunological alterations with increase...
Down syndrome (DS) resembles immunodeficiency with increased infections, auto-immune diseases, and h...
Background: Down's syndrome (DS) patients present a high risk of developing alterations of the immun...
Immune defects, thyroid abnormalities, infections and coeliac disease are often associated with Down...
Individuals with Down syndrome (US) suffer from increased incidence of respiratory infections and ly...
PubMedID: 20477881The objective of this study was to evaluate the relationship between humoral and c...
Down syndrome (DS), the most common chromosomal abnormality in humans, is characterized by precociou...
Down syndrome (DS) is associated with increased susceptibility to infections, auto-immunity, immunod...
AbstractDifferent types of cells from subjects with Down syndrome (DS) have an increased susceptibil...
Phenotype and proliferative ability of peripheral blood lymphocytes from 15 noninstitutionalized chi...
Different types of cells from subjects with Down syndrome (DS) have an increased susceptibility to c...
Phenotype and proliferative ability of peripheral blood lymphocytes from 15 noninstitutionalized chi...
AbstractIt is hypothesized that Down syndrome (DS) patients are associated with abnormalities of the...
Children with Down syndrome (DS) have increased susceptibility to infections and a high frequency of...
Individuals with Down syndrome (DS) have a high incidence of immunological alterations with increase...
Individuals with Down syndrome (DS) have a high incidence of immunological alterations with increase...