In this paper I stage an encounter between two concepts that have become popular placeholders for a broad concern with a politics of life: affect and biopower. Through engagement with Antonio Negri’s writings on the ‘real subsumption of life’ in contemporary capitalism and Michel Foucault’s lectures on neo-liberalism, I show that understanding how forms of biopower work through affect requires attending to three relations: affective relations and capacities are object-targets for discipline, biopolitics, security, and environmentality; affective life is the outside through which new ways of living may emerge; and specific collective affects (including ‘state-phobia’) are part of the conditions for the birth of forms of biopower. In what is ...