Nano-analytical characterization of endogenous minerals in healthy placental tissue: mineral distribution, composition and ultrastructure
- Anthis, A. H. C.
- Tsolaki, Elena
- Didierlaurent, Louis
- Staubli, Samuel
- Zboray, Robert
- Neels, Antonia
- Dietrich, Dörthe
- Manser, Pius
- Desbiolles, Lotus May
- Leschka, Sebastian
- Wildermuth, Simon
- Lehner, Sandro
- Chavatte-Palmer, Pascale
- Jochum, Wolfram
- Wick, Peter
- Dommann, Alex
- Bürki-Turnherr, Tina
- Fischer, Tina
- Hornung, René
- Bertazzo, Sergio
- Herrmann, Inge K.
DOIAbstract
Despite its crucial role, the placenta is the least understood human organ. Recent clinical studies indicate a direct association between placental calcification and maternal and offspring health. This study reveals distinct characteristics of minerals formed during gestational ageing using cutting-edge nano-analytical characterization and paves the way for investigations focused on the identification of potential markers for disease risks in a clinical setting based on atypical placental mineral fingerprints
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