PURPOSE: This study explores the potential of the simvastatin to ameliorate inflammation and infection in open infected skin wounds of rats. METHODS: Fourteen Wistar rats weighing 285±12g were used. The study was done in a group whose open infected skin wounds were treated with topical application of sinvastatina microemulsion (SIM, n=7) and a second group with wounds treated with saline 0.9 % (SAL, n=7). A bacteriological exam of the wounds fluid for gram positive and gram negative bacteria, the tecidual expression of TNFá and IL-1â by imunohistochemical technique, and histological analysis by HE stain were performed. RESULTS: The expression of TNFa could be clearly demonstrated in lower degree in skin wounds treated with simvastati...
Estudo experimental em animais. A mitomicina C vem sendo usada como inibidor de fibroblastos, acarre...
Analisar se o pré-tratamento com sinvastatina em modelo experimental de sepse abdominal é benéfico e...
Recent research suggests that statins might be useful in the process of wound healing, playing a pos...
This study explores the potential of the simvastatin to ameliorate inflammation and infection in ope...
PURPOSE: This study explores the potential of the simvastatin to ameliorate inflammation and infecti...
ABSTRACT Purpose: Statins are widely recognized as hypolipemic drugs, but some studies have observed...
PURPOSE: Statins are widely recognized as hypolipemic drugs, but some studies have observed anti-inf...
Background: Inflammation is a complex reaction in tissues that consists mainly of response of blood ...
Wounds and wound healing have always been one of the most important subjects that experimental resea...
CNPQ – CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO CIENTÍFICO E TECNOLÓGICOFAPESP...
Oral cavity wound is encountered frequently in dental clinics. Simvastatin has been used for long as...
Annual Congress on Turkish National Surgery -- MAY, 2008 -- Antalya, TURKEYWOS: 000268575000024PubMe...
Staphylococcus aureus is one of the most prevalent etiologic agents causing sepsis, a systemic infla...
PURPOSE: To investigate the effect of prophylactic dose of a low molecular weight heparin, enoxapari...
ABSTRACT Objective: simvastatin has pleiotropic anti-inflammatory and immunomodulatory effects pote...
Estudo experimental em animais. A mitomicina C vem sendo usada como inibidor de fibroblastos, acarre...
Analisar se o pré-tratamento com sinvastatina em modelo experimental de sepse abdominal é benéfico e...
Recent research suggests that statins might be useful in the process of wound healing, playing a pos...
This study explores the potential of the simvastatin to ameliorate inflammation and infection in ope...
PURPOSE: This study explores the potential of the simvastatin to ameliorate inflammation and infecti...
ABSTRACT Purpose: Statins are widely recognized as hypolipemic drugs, but some studies have observed...
PURPOSE: Statins are widely recognized as hypolipemic drugs, but some studies have observed anti-inf...
Background: Inflammation is a complex reaction in tissues that consists mainly of response of blood ...
Wounds and wound healing have always been one of the most important subjects that experimental resea...
CNPQ – CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO CIENTÍFICO E TECNOLÓGICOFAPESP...
Oral cavity wound is encountered frequently in dental clinics. Simvastatin has been used for long as...
Annual Congress on Turkish National Surgery -- MAY, 2008 -- Antalya, TURKEYWOS: 000268575000024PubMe...
Staphylococcus aureus is one of the most prevalent etiologic agents causing sepsis, a systemic infla...
PURPOSE: To investigate the effect of prophylactic dose of a low molecular weight heparin, enoxapari...
ABSTRACT Objective: simvastatin has pleiotropic anti-inflammatory and immunomodulatory effects pote...
Estudo experimental em animais. A mitomicina C vem sendo usada como inibidor de fibroblastos, acarre...
Analisar se o pré-tratamento com sinvastatina em modelo experimental de sepse abdominal é benéfico e...
Recent research suggests that statins might be useful in the process of wound healing, playing a pos...