Background: ATP-binding cassette transporter ABCG8 plays an important role in excretion of cholesterol from liver. Common genetic polymorphisms in ABCG8 gene may genetically predispose an individual to coronary artery disease (CAD) along with response to atorvastatin therapy. Thus, we aimed to examine the role of ABCG8 D19H polymorphism (rs11887534) in susceptibility to CAD and its influence on atorvastatin response
Numerous epidemiological studies have evaluated the associations between ATP-binding cassette transp...
Purpose Simvastatin and atorvastatin are metabolized by the CYP3A4 enzyme and transported by the ABC...
Objective— Loss-of-function mutations of the ATP-binding cassette transporter A1 (ABCA1) gene cause ...
ATP-binding cassette transporter A1 (ABCA1) has a crucial role in removing intracellular cholesterol...
Elevated plasma plant sterol concentrations may be a risk factor of cardiovascular disease (CVD). Po...
Elevated plasma plant sterol concentrations may be a risk factor of cardiovascular disease (CVD). Po...
Abstract Background Drug response is below genetic influence, proven by the genetic variants. Pharma...
Objective—ATP binding cassette transporter G1 (ABCG1) facilitates cholesterol efflux from macrophage...
BACKGROUND: ATP - binding cassette transporter A1 (ABCA1) plays essential roles in the biogenesis of...
Background: TheI823M polymorphism of the ATP-binding cassette transporter A1 (ABCA1) gene has been r...
This study investigated the effects of atorvastatin on ABCB1 and ABCC1 mRNA expression on peripheral...
To test the hypothesis that ABCA1 gene common variants are genetic factors that influence lipid leve...
Coronary artery disease is among the leading causes of death worldwide. Clinical trials show a prote...
Background: Defects of lipoprotein metabolism are common risk factors for coronary artery disease. T...
Several statins are substrates for the multidrug resistance-associated protein 2 transporter, encode...
Numerous epidemiological studies have evaluated the associations between ATP-binding cassette transp...
Purpose Simvastatin and atorvastatin are metabolized by the CYP3A4 enzyme and transported by the ABC...
Objective— Loss-of-function mutations of the ATP-binding cassette transporter A1 (ABCA1) gene cause ...
ATP-binding cassette transporter A1 (ABCA1) has a crucial role in removing intracellular cholesterol...
Elevated plasma plant sterol concentrations may be a risk factor of cardiovascular disease (CVD). Po...
Elevated plasma plant sterol concentrations may be a risk factor of cardiovascular disease (CVD). Po...
Abstract Background Drug response is below genetic influence, proven by the genetic variants. Pharma...
Objective—ATP binding cassette transporter G1 (ABCG1) facilitates cholesterol efflux from macrophage...
BACKGROUND: ATP - binding cassette transporter A1 (ABCA1) plays essential roles in the biogenesis of...
Background: TheI823M polymorphism of the ATP-binding cassette transporter A1 (ABCA1) gene has been r...
This study investigated the effects of atorvastatin on ABCB1 and ABCC1 mRNA expression on peripheral...
To test the hypothesis that ABCA1 gene common variants are genetic factors that influence lipid leve...
Coronary artery disease is among the leading causes of death worldwide. Clinical trials show a prote...
Background: Defects of lipoprotein metabolism are common risk factors for coronary artery disease. T...
Several statins are substrates for the multidrug resistance-associated protein 2 transporter, encode...
Numerous epidemiological studies have evaluated the associations between ATP-binding cassette transp...
Purpose Simvastatin and atorvastatin are metabolized by the CYP3A4 enzyme and transported by the ABC...
Objective— Loss-of-function mutations of the ATP-binding cassette transporter A1 (ABCA1) gene cause ...