Changes in some biochemical parameters accompanied with brucellosis in sheep

The aim of the present study was to determine seroprevalence of brucellosis in serum of non vaccinated sheep by using different serological tests, Rose Bengal test, tube agglutination test and indirect ELISA test, in addition to study of changes in some biochemical parameters accompanied with Brucellosis in sheep. Study included examination of 228 blood serum samples in different areas of Mosul city. Results showed that prevalence of Brucellosis by using rose Bengal test and indirect ELISA test was (8.77% and 23.6%) respectively. Titers of seropostive sera of Rose Bengal and indirect ELISA ranged (1/40 - 1/640) using tube agglutination test. Results also showed significant increased in aspartate transaminase, alanin transaminase, lactate dehydrogenase, alkaline phosphatase, in addition to significant increase in glucose concentration, total bilirubin, direct bilirubin, triglycerides and cholesterol, whereas total protein and albumin values significantly decreased. All these parameters examinated on seropostive sera for indirect ELISA and tube agglutination tests in sheep naturally infected with Brucellosis compared with seronegative sera for same tests