The reaction of indole with chalcones, to give Michael-type adducts, was found to occur with good efficiency (up to 98% yield) and moderate enantioselectivity (up to 52% e.e.) in the presence of a chiral BINOL-based phosphoric acid. Furthermore, the alkylation products can be obtained in much higher e.e.s after one only crystallization
The first intermolecular organocatalytic enantioselective addition of indoles to prochiral 5-membere...
The first intermolecular organocatalytic enantioselective addition of indoles to prochiral 5-membere...
International audienceThe first intermolecular organocatalytic enantioselective addition of indoles ...
The reaction of indole with chalcones, to give Michael-type adducts, was found to occur with good ef...
Tritylsulfenyl- and 2-nitrophenylsulfenyl-substituted glyoxyl imines were used in chiral phosphoric ...
Fiaud’s acid (<i>trans</i>-1-hydroxy-2,5-diphenylphospholane 1-oxide), a phospholane-based phosphini...
A highly enantioselective C2 Friedel–Crafts alkylation reaction of 3-substituted indoles to β,γ-unsa...
The asymmetric Friedel–Crafts alkylation reactions of indoles with β-substituted cyclopentenimines e...
An enantioconvergent Friedel–Crafts alkylation of indoles with donor–acceptor cyclopropanes is descr...
An enantioselective intramolecular dearomative Michael addition of indolyl enones is presented. In t...
The first intermolecular organocatalytic enantioselective addition of indoles to prochiral 5-membere...
The first intermolecular organocatalytic enantioselective addition of indoles to prochiral 5-membere...
International audienceThe first intermolecular organocatalytic enantioselective addition of indoles ...
International audienceThe first intermolecular organocatalytic enantioselective addition of indoles ...
International audienceThe first intermolecular organocatalytic enantioselective addition of indoles ...
The first intermolecular organocatalytic enantioselective addition of indoles to prochiral 5-membere...
The first intermolecular organocatalytic enantioselective addition of indoles to prochiral 5-membere...
International audienceThe first intermolecular organocatalytic enantioselective addition of indoles ...
The reaction of indole with chalcones, to give Michael-type adducts, was found to occur with good ef...
Tritylsulfenyl- and 2-nitrophenylsulfenyl-substituted glyoxyl imines were used in chiral phosphoric ...
Fiaud’s acid (<i>trans</i>-1-hydroxy-2,5-diphenylphospholane 1-oxide), a phospholane-based phosphini...
A highly enantioselective C2 Friedel–Crafts alkylation reaction of 3-substituted indoles to β,γ-unsa...
The asymmetric Friedel–Crafts alkylation reactions of indoles with β-substituted cyclopentenimines e...
An enantioconvergent Friedel–Crafts alkylation of indoles with donor–acceptor cyclopropanes is descr...
An enantioselective intramolecular dearomative Michael addition of indolyl enones is presented. In t...
The first intermolecular organocatalytic enantioselective addition of indoles to prochiral 5-membere...
The first intermolecular organocatalytic enantioselective addition of indoles to prochiral 5-membere...
International audienceThe first intermolecular organocatalytic enantioselective addition of indoles ...
International audienceThe first intermolecular organocatalytic enantioselective addition of indoles ...
International audienceThe first intermolecular organocatalytic enantioselective addition of indoles ...
The first intermolecular organocatalytic enantioselective addition of indoles to prochiral 5-membere...
The first intermolecular organocatalytic enantioselective addition of indoles to prochiral 5-membere...
International audienceThe first intermolecular organocatalytic enantioselective addition of indoles ...