Crevicular Fluid Level Of Beta-Glukuronidase In Type I And Type II Diabetes Mellitus Patients

Beta- glukuronidase activity in pocket fluid samples were taken from 120 patients divided into 4 groups. The groups were identified as Type I DM (Diabetes Mellitus) metabolic uncontrolled, Type I metabolic controlled, Type II metabolic controlled and Type II metabolic controlled groups. Beta- glukuronidase levels of the GCF samples taken from the subject were analyzed using the spectrophotometric method. GCF beta- glukuronidase levels in terms of total enzyme activity and total enzyme concentration, were found to be higher in the uncontrolled metabolic diabetic groups than in the controlled metabolic diabetic groups.The findings in this study indicate that in patients with diabetics, metabolic control levels play a role on the health of periodontal tissues. We have reached the conclusion that uncontrolled diabet is a potential risk factor in the aggressiveness of the periodontal disease