Aim. To evaluate whether the combination of the peripheral blood CD4+ adenosine triphosphate activity (ATP) assay (ImmuKnow assay: IMK assay) and cytochrome P450 3A5 (CYP3A5) genotype assay is useful for monitoring of immunological aspects in the patient followup of more than one year after living donor liver transplantation (LDLT). Methods. Forty-nine patients, who underwent LDLT more than one year ago, were randomly screened by using IMK assay from January 2010 to December 2011, and the complete medical records of each patient were obtained. The CYP3A5 genotypes were examined in thirty-nine patients of them. Results. The mean ATP level of the IMK assay was significantly lower in the patients with infection including recurrence of hepatiti...
The immune function test is an integrated measure of total mitogen-inducible CD4(+) T cell metabolic...
Background: The impact of cytochrome P450 3A5 (CYP3A5) genotype of recipients (intestine) as well as...
A fraction of liver transplant recipients are able to discontinue all immunosuppressive therapies wi...
Seventy living donor liver transplantation (LDLT) and 39 kidney transplantation (KT) patients were r...
Aim: The ImmuKnow (IK) assay enables the evaluation of peripheral blood CD4+ adenosine triphosphate ...
Copyright © 2013 Yu Nobuoka et al. This is an open access article distributed under the Creative Com...
Background: Liver transplantation is a curative method for end-stage liver diseases, small unresect...
Conventional assays for quantification of allo-reactive T-cell precursor frequencies (PF) are relati...
textabstractConventional assays for quantification of allo-reactive T-cell precursor frequencies (PF...
The validation of reliable, non-invasive immunological assays evaluating anti-donor responsiveness i...
Operational tolerance (graft acceptance in an immunosuppression (IS)-free environment) after living-...
A fraction of liver transplant recipients are able to discontinue all immunosuppressive therapies wi...
Liver transplantation (LT) has become the only curative treatment for end-stage liver disease. Patie...
In 45 liver transplant recipients, the value of weekly monitoring of cytomegalovirus (CMV) antigenem...
infection is a common complication in transplant recipients. Sensitive, specific and timely diagnost...
The immune function test is an integrated measure of total mitogen-inducible CD4(+) T cell metabolic...
Background: The impact of cytochrome P450 3A5 (CYP3A5) genotype of recipients (intestine) as well as...
A fraction of liver transplant recipients are able to discontinue all immunosuppressive therapies wi...
Seventy living donor liver transplantation (LDLT) and 39 kidney transplantation (KT) patients were r...
Aim: The ImmuKnow (IK) assay enables the evaluation of peripheral blood CD4+ adenosine triphosphate ...
Copyright © 2013 Yu Nobuoka et al. This is an open access article distributed under the Creative Com...
Background: Liver transplantation is a curative method for end-stage liver diseases, small unresect...
Conventional assays for quantification of allo-reactive T-cell precursor frequencies (PF) are relati...
textabstractConventional assays for quantification of allo-reactive T-cell precursor frequencies (PF...
The validation of reliable, non-invasive immunological assays evaluating anti-donor responsiveness i...
Operational tolerance (graft acceptance in an immunosuppression (IS)-free environment) after living-...
A fraction of liver transplant recipients are able to discontinue all immunosuppressive therapies wi...
Liver transplantation (LT) has become the only curative treatment for end-stage liver disease. Patie...
In 45 liver transplant recipients, the value of weekly monitoring of cytomegalovirus (CMV) antigenem...
infection is a common complication in transplant recipients. Sensitive, specific and timely diagnost...
The immune function test is an integrated measure of total mitogen-inducible CD4(+) T cell metabolic...
Background: The impact of cytochrome P450 3A5 (CYP3A5) genotype of recipients (intestine) as well as...
A fraction of liver transplant recipients are able to discontinue all immunosuppressive therapies wi...