Purpose : to identify and substantiate medico-biological, psychological and social problems of doping in sport. Material: Theoretical study is based on analysis of more than 50 scientific and methodical literatures. Results : it was shown that doping is one of the serious problems of modern sport and society in general. Defines important questions regarding anti-doping rules and the anti-doping control in sport. Installed the use of performance enhancing drugs in professional sports for children and youth. Given the promising solutions to the problems of doping in Ukraine. Conclusions: Among the problems of modern sport is becoming increasingly important issue of doping. It is an extremely complex because it involves the interrelated medica...