Add to ORKGAim: This study has been to evaluate the level of membrane potential and electrolyte in sickle cell disease patients. Material and methods: 100 sickle cell patients in steady state ages 5 to 30 years attending General Hospital Owerri were used in the study while 100 normal subjects (HbAA) were used as control. Also 30 HbSS in crisis have been involved. Results: The results obtained showed that the level of membrane potential was significantly lower in sickle cell anemia as compared to the controls. Also, the level of the electrolyte was found significantly decreased in HbSS when compared with HbAA at P<0.05. Conclusion: The membrane potential translates to energy which means that there is less energy in sickle cell disease whic...
Background: Sickle cell disease was a genetic pathology of the red blood cell, which caused systemic...
In sickle cell disease, in the homozygous state, the increased heterogeneity of erythrocytes results...
A homozygous mutation in the gene for b globin, a subunit of adult hemoglobin A (HbA), is the proxim...
Background: Sickle cell disease is a common genetic disorder mainly characterized by vascular occlus...
BACKGROUND: Sickle cell anaemia (SCA) patients are prone to electrolyte imbalance and derangement of...
Background: Cells with markedly increased Haemoglobin concentration are a prominent feature of sickl...
Background: Sickle-cell anaemia is an inherited disease in which genes for sickle-cell haemoglobin c...
Sickle Cell Disease is inherited genetic disease. An autosomal recessive gene is responsible for the...
Erythrocyte sodium (Na+), potassium (K+) as well as plasma Na+, K+, chloride (C-) bicarbonate (HCO3-...
Oxidative damage to red blood cells (RBCs) may contribute to pathogenesis of sickle cell anemia. Red...
The early stages of sickle cell nephropathy manifest in children with sickle cell anemia as hyperfil...
Background/Aims: Kidney abnormalities are one of the main chronic complications of sickle cell disea...
Current knowledge on the pathophysiology of sickle cell anemia is reviewed and potential therapeutic...
Vaso-occlusive pain crisis is the hallmark complication of sickle cell anemiaand may be precipitated...
Background: Sickle cell anaemia is a hemoglobinopathy with the production of abnormal hemoglobin, Hb...
Background: Sickle cell disease was a genetic pathology of the red blood cell, which caused systemic...
In sickle cell disease, in the homozygous state, the increased heterogeneity of erythrocytes results...
A homozygous mutation in the gene for b globin, a subunit of adult hemoglobin A (HbA), is the proxim...
Background: Sickle cell disease is a common genetic disorder mainly characterized by vascular occlus...
BACKGROUND: Sickle cell anaemia (SCA) patients are prone to electrolyte imbalance and derangement of...
Background: Cells with markedly increased Haemoglobin concentration are a prominent feature of sickl...
Background: Sickle-cell anaemia is an inherited disease in which genes for sickle-cell haemoglobin c...
Sickle Cell Disease is inherited genetic disease. An autosomal recessive gene is responsible for the...
Erythrocyte sodium (Na+), potassium (K+) as well as plasma Na+, K+, chloride (C-) bicarbonate (HCO3-...
Oxidative damage to red blood cells (RBCs) may contribute to pathogenesis of sickle cell anemia. Red...
The early stages of sickle cell nephropathy manifest in children with sickle cell anemia as hyperfil...
Background/Aims: Kidney abnormalities are one of the main chronic complications of sickle cell disea...
Current knowledge on the pathophysiology of sickle cell anemia is reviewed and potential therapeutic...
Vaso-occlusive pain crisis is the hallmark complication of sickle cell anemiaand may be precipitated...
Background: Sickle cell anaemia is a hemoglobinopathy with the production of abnormal hemoglobin, Hb...
Background: Sickle cell disease was a genetic pathology of the red blood cell, which caused systemic...
In sickle cell disease, in the homozygous state, the increased heterogeneity of erythrocytes results...
A homozygous mutation in the gene for b globin, a subunit of adult hemoglobin A (HbA), is the proxim...