Ever since the discovery of aspirin, small molecule therapeutics have been widely prescribed to treat inflammation and pain. Aspirin and several small molecule NSAIDs are known to inhibit the enzymes cyclooxygenase-1 (COX-1) and -2 (COX-2). Despite the success of NSAIDs to treat inflammatory disorders, the development of a clinically useful small molecule NSAIDs with decreased side effect profiles is an ongoing effort. The recent discovery and development of selective COX-2 inhibitors was a step toward this direction. Emerging trends are represented by the progress in the development of hybrid agents such as nitric oxide donor-NSAIDs (NO-NSAIDs) and dual COX/lipoxygenase (LOX) inhibitors. This review focuses on the recent advances in the ra...
Drugs able to inhibit both cyclooxygenases (COX-1 and COX-2) and 5-lipoxygenase (5-LOX) (dual acting...
The discovery of two isoforms of the cyclooxygenase enzyme, COX-1 and COX-2, and the development of ...
Inflammation is a natural process that is connected to various conditions and disorders such as arth...
Ever since the discovery of aspirin, small molecule therapeutics have been widely prescribed to trea...
ABSTRACTRecent advances in basic and clinical researches of nonsteroidal anti-inflammatory drugs (NS...
This study includes design and synthesis of new non-steroidal anti-inflammatory agents (NSAIDs) with...
Nonsteroidal anti-inflammatory drugs (NSAIDs) reversibly inhibit the functioning of cyclooxygenase (...
Nonsteroidal anti-inflammatory drugs (NSAIDs) are a mainstay in the treatment of inflammatory diseas...
Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most widely used medications-both prescr...
Kay Brune,1 Paola Patrignani2 1Department of Experimental and Clinical Pharmacology and Toxicology, ...
Non steroidal anti-inflammatory drugs (NSAIDs) are still the most commonly used remedies for rheumat...
Non steroidal anti-inflammatory drugs (NSAIDs) are still the most commonly used remedies for rheumat...
Inflammation involving the innate and adaptive immune systems is a normal response to infection. How...
In this short review we have tried to focus on some new relevant aspects of the pharmacological cont...
Nonsteroidal anti-inflammatory drugs (NSAIDs) are some of the most widely prescribed or dispensed an...
Drugs able to inhibit both cyclooxygenases (COX-1 and COX-2) and 5-lipoxygenase (5-LOX) (dual acting...
The discovery of two isoforms of the cyclooxygenase enzyme, COX-1 and COX-2, and the development of ...
Inflammation is a natural process that is connected to various conditions and disorders such as arth...
Ever since the discovery of aspirin, small molecule therapeutics have been widely prescribed to trea...
ABSTRACTRecent advances in basic and clinical researches of nonsteroidal anti-inflammatory drugs (NS...
This study includes design and synthesis of new non-steroidal anti-inflammatory agents (NSAIDs) with...
Nonsteroidal anti-inflammatory drugs (NSAIDs) reversibly inhibit the functioning of cyclooxygenase (...
Nonsteroidal anti-inflammatory drugs (NSAIDs) are a mainstay in the treatment of inflammatory diseas...
Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most widely used medications-both prescr...
Kay Brune,1 Paola Patrignani2 1Department of Experimental and Clinical Pharmacology and Toxicology, ...
Non steroidal anti-inflammatory drugs (NSAIDs) are still the most commonly used remedies for rheumat...
Non steroidal anti-inflammatory drugs (NSAIDs) are still the most commonly used remedies for rheumat...
Inflammation involving the innate and adaptive immune systems is a normal response to infection. How...
In this short review we have tried to focus on some new relevant aspects of the pharmacological cont...
Nonsteroidal anti-inflammatory drugs (NSAIDs) are some of the most widely prescribed or dispensed an...
Drugs able to inhibit both cyclooxygenases (COX-1 and COX-2) and 5-lipoxygenase (5-LOX) (dual acting...
The discovery of two isoforms of the cyclooxygenase enzyme, COX-1 and COX-2, and the development of ...
Inflammation is a natural process that is connected to various conditions and disorders such as arth...