Isolation of a new HIV-2 group in the US
- Gautam Aarti
- Gautam Rajeev
- Austin Louise
- Shah Urvi
- de Lame Valéry
- Christian Deanna
- Smith Stephen M
- Apetrei Cristian
- Marx Preston A
Publication date
November 2008
DOI Publisher
Springer Science and Business Media LLC Journal
RetrovirologyAbstract
Abstract Human immunodeficiency virus type 2 (HIV-2) emerged following cross-species transmission of simian immunodeficiency virus (SIV) from sooty mangabeys to humans several decades ago. The epidemic groups of HIV-2 have been established in the human population for at least 50 years. However, it is likely that new divergent SIVs can infect humans and lead to new outbreaks. We report the isolation of a new strain of HIV-2, HIV2-NWK08F, from an immunodeficient Sierra Leone immigrant. Health care providers in Sierra Leone and elsewhere need to be alerted that a subtype of HIV-2, which is not detected by PCR for epidemic HIV-2 strains, exists and can lead to immunosuppression.</p
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