Add to ORKGPapillon-Lefevre syndrome is a rare (1-4 cases per million) autosomal recessive disorder showing predominantly oral and dermatological manifestations in the form of aggressive periodontitis affecting both primary and permanent dentition and palmoplantar hyperkeratosis. Genetic studies have shown that mutations in the major gene locus of chromosome 11q14 with loss of function of cathepsin C gene are responsible for Papillon-Lefevre syndrome. This report presents two siblings with classic signs and symptoms of Papillon-Lefevre syndrome. The exact cause for periodontal destruction in patients with Papillon-Lefevre syndrome is not known but it is thought to be due to defect in neutrophil function, immune suppression and mutations in cathepsin C...
Introduction: Papillon-Lefèvre syndrome is a rare autosomal recessive disorder. This syndrome is cha...
Papillon-Lefèvre syndrome is an extremely rare genodermatosis inherited as an autosomal recessive tr...
Papillion-Lefèvre Syndrome is a very rare disorder of autosomal recessive inheritance distinguished ...
Papillon Lefevre syndrome is an extremely rare autosomal recessive disorder characterized by diffuse...
A rare autosomal recessive disease Papillon lefevre syndrome is caused by mutation in the cathepsin ...
Papillon-Lefevre syndrome (PLS) is an autosomal recessive disorder characterised by palmoplantar hyp...
Papillon-Lefevre syndrome (PLS) is an inherited human disease characterized by early-onset periodont...
Papillon-Lefevre Syndrome (PLS) is a autosomal recessive genetic disorder. The prevalence of this di...
Papillon-Lefevre Syndrome (PLS) is a autosomal recessive genetic disorder. The prevalence of this di...
Introduction-Papillon-Lefevre syndrome (PLS) is an autosomal recessive disorder characterised by pal...
The Papillon-Lefevre syndrome is a rare autosomal recessive disorder. Consanguinity seems a notable ...
Papillon-Lefevre syndrome is an autosomal recessive genodermatosis typically manifesting with the co...
Papillon-Lefevre syndrome (PLS) is a rare autosomal recessive disorder characterized by the associat...
Papillon-Lefevre syndrome (PLS) is a very rare syndrome of autosomal recessive inheritance character...
Papillon-Lefevre syndrome is a rare autosomal recessively inherited condition which shows features c...
Introduction: Papillon-Lefèvre syndrome is a rare autosomal recessive disorder. This syndrome is cha...
Papillon-Lefèvre syndrome is an extremely rare genodermatosis inherited as an autosomal recessive tr...
Papillion-Lefèvre Syndrome is a very rare disorder of autosomal recessive inheritance distinguished ...
Papillon Lefevre syndrome is an extremely rare autosomal recessive disorder characterized by diffuse...
A rare autosomal recessive disease Papillon lefevre syndrome is caused by mutation in the cathepsin ...
Papillon-Lefevre syndrome (PLS) is an autosomal recessive disorder characterised by palmoplantar hyp...
Papillon-Lefevre syndrome (PLS) is an inherited human disease characterized by early-onset periodont...
Papillon-Lefevre Syndrome (PLS) is a autosomal recessive genetic disorder. The prevalence of this di...
Papillon-Lefevre Syndrome (PLS) is a autosomal recessive genetic disorder. The prevalence of this di...
Introduction-Papillon-Lefevre syndrome (PLS) is an autosomal recessive disorder characterised by pal...
The Papillon-Lefevre syndrome is a rare autosomal recessive disorder. Consanguinity seems a notable ...
Papillon-Lefevre syndrome is an autosomal recessive genodermatosis typically manifesting with the co...
Papillon-Lefevre syndrome (PLS) is a rare autosomal recessive disorder characterized by the associat...
Papillon-Lefevre syndrome (PLS) is a very rare syndrome of autosomal recessive inheritance character...
Papillon-Lefevre syndrome is a rare autosomal recessively inherited condition which shows features c...
Introduction: Papillon-Lefèvre syndrome is a rare autosomal recessive disorder. This syndrome is cha...
Papillon-Lefèvre syndrome is an extremely rare genodermatosis inherited as an autosomal recessive tr...
Papillion-Lefèvre Syndrome is a very rare disorder of autosomal recessive inheritance distinguished ...