Is adiponectin associated with acute myocardial infarction in Iranian non obese patients?

Abstract Backgrounds Adiponectin is an adipose tissue-derived mediator with significant anti-atherogenic properties. A few studies were done in acute phase of myocardial infarction especially in non obese patients. We design a study to investigate the association between adiponectin concentration and acute phase of myocardial infarction in non obese patients. Methods This case-control study was done in Paymaneah Hospital (Jahrom, Iran) from Feb 2007 to May 2008. Plasma adiponectin levels were measured in 43 patients with AMI (mean age: 62.7 ± 13.3 years, male: 67.4%) at the first 24 hours of admission and 43 normal controls (mean age: 62.1 ± 12.3 years, male: 55.8%) matched for age, sex and other CAD risk factors. Results Adiponectin levels in patients with AMI (3.36 μg/mL) were significantly lower than that of the control group (5.03 μg/mL) (p Conclusion The present study showed that adiponectin was associated with AMI in non obese patients but it is not related to sex, age and other CAD risk factors.