Ion Channels and Their Roles on The Pathogenesis of Epilepsy

Ion channels especially nicotinic acethylcholine receptor channels, potassium and sodium channels play roles in the physiopathology of various types of epilepsies. They play vital roles in either providing membrane potential and in neuronal signaling. In this review, first, information about the structure and function of ion channels and then how the structure and functions of subunits of them change within a neurological disease like epilepsy will be given. [Archives Medical Review Journal 2010; 19(2.000): 72-84