Low frequency low intensity pulse electromagnetic filed in vivo influence on immune capacity in rat

plied continuously 30 min for a period of 20 days, upon the immune reactivity in rats was studied. For this aim, leukocytes, antibody titer, the albumin/globulin ratio were determined by appropriate methods in rats treated with PEMF under normal conditions, under stress conditions of isolation and under sulpiride treatment as dopamine D2 receptor blocking agent. Isolation stress induced an increase of leukocytes total number and a leucocyte formula modification, which indicates an attempt to increase the cellular mediated body defense capacity of the stressed organism. Also, the stress of isolation reduces the amount of antibody, which means a possible reduction of humoral mediated defense capability. However, under stress of isolation an increase of albumin/globulin ratio values were observed. PEMF treatment induces a recovery trend of antibody titer and leucocyte formula values. PEMF combined with sulpiride and isolation stress treatment determined recovery of albumin/globulin ratio, indicating an antistress effect of PEMF treatment, which is achieved probably through D2-dopamine receptor