Effect of phacoemulsification on corneal endothelium of cataract with lupus nephritis

AIM:To evaluate the influence of phacoemulsification on corneal endothelium of senile cataract with lupus nephritis(LN). METHODS:This clinical trial involved 40 cataract patients with lupus nephritis(40 eyes), and 50 cases(50 eyes)without lupus nephritis. All of them underwent phacoemulsification+IOL implantation. The parameters of corneal endothelial cell including central corneal endothelium cell density(CED),average area of endothelial cell(AVE)and coefficient of variation(CV)were recorded by corneal endothelial microscope pre-operation and at one month after operation. The data were analyzed by SPSS 13.0 statistical software.RESULTS:Both LN group and control group, the morphology of coneal endothelial was statistical significant differences between pre-operation and 1mo postoperation. The CED was lower, AVE and CV were higher(PPPCONCLUSION:The corneal endothelial cell in lupus nephritis patients is more fragile. Safe and reliable operation should be selected for these patients