Interconnections between type II superstrings, M theory and N=4 supersymmetric Yang-Mills

These lecture notes begin with a review of the first nonleading contributions to the derivative expansion of the M theory effective action compactified on a two-torus. The form of these higher-derivative interactions is shown to follow from ten-dimensional type IIB supersymmetry as well as from one-loop quantum corrections to classical eleven-dimensional supergravity. The detailed information concerning D-instanton effects encoded in these terms is related to the problem of evaluating the Witten index for $N$ D-particles in the type IIA theory. Using the AdS/CFT conjecture, it also leads to very specific predictions of multi-instanton contributions in $\cal N=4$ supersymmetric SU(N) Yang--Mills theory in the limit of strong 't Hooft coupling. [Extended version of lectures given at 22nd Johns Hopkins Workshop (Gothenberg, August 20-22 1998); `Quantum Aspects of Gauge Theories, Supersymmetry and Unification', TMR meeting (Corfu, September 20-26 1998); Andrjewski lectures (Berlin, November 1-6 1998).