Detection of human parvovirus B19 in serum samples from children under 5 years of age with rash-fever illnesses in the Democratic Republic of the Congo
- Wawina, Tony Bokalanga
- Tshiani, Olivier Mbaya
- Ahuka, Steve Mundeke
- Pukuta, Elisabeth Simbu
- Aloni, Michel Ntetani
- Kasanga, Christopher Jacob
- Muyembe, Jean-Jacques Tamfum
DOIAbstract
BACKGROUND: It has been demonstrated that infection with human parvovirus B19 (B19V) is associated with rash-fever illnesses. The present study aimed to investigate B19V as an aetiological agent of rash-fever syndromes in Congolese children confirmed as measles and rubella IgM-negative. An ELISA IgM test and PCR were performed to screen for B19V. METHODS: A total of 177 archived serum samples were randomly selected from the measles biobank of the National Institute for Biomedical Research (INRB). Samples were investigated for anti-B19V IgM and B19V DNA. These samples originated from children <5years of age with measles-like rashes, previously confirmed as negative for both measles and rubella IgM. RESULTS: Out of 177 serum samples tested by...
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