Molecular Subtypes of Clear-cell Renal Cell Carcinoma are Prognostic for Outcome After Complete Metastasectomy
- Verbiest, Annelies
- Couchy, Gabrielle
- Job, Sylvie
- Caruana, Laure
- Lerut, Evelyne
- Oyen, Raymond
- de Reyniès, Aurélien
- Tosco, Lorenzo
- Joniau, Steven
- Van Poppel, Hendrik
- Van Raemdonck, Dirk
- Van den Eynde, Kathleen
- Wozniak, Agnieszka
- Zucman-Rossi, Jessica
- Beuselinck, Benoit
Publication date
October 2018
DOI Publisher
Elsevier BV Journal
European UrologyAbstract
Metastasectomy is routinely performed in selected patients with metastatic clear-cell renal cell carcinoma (ccRCC) as an alternative to systemic therapy. In the absence of randomized trials, the benefit and best way of patient selection remain unclear. Earlier, we described four molecular ccRCC-subtypes (ccrcc1-4) that have a prognostic and predictive value upon first-line sunitinib or pazopanib.status: publishe
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