Obesity Impairs Oligopeptide/Amino Acid-Induced Ghrelin Release and Smooth Muscle Contractions in the Human Proximal Stomach
- Vancleef, Laurien
- Thijs, Theo
- Baert, Florence
- Ceulemans, Laurens
- Canovai, Emilio
- Wang, Qiaoling
- Steensels, Sandra
- Segers, Anneleen
- Farre, Ricard
- Pirenne, Jacques
- Lannoo, Matthias
- Tack, Jan
- Depoortere, Inge
Publication date
March 2018
DOI Publisher
Wiley Journal
Molecular Nutrition & Food ResearchAbstract
The satiation properties of proteins involve effects on gut peptide release and gastrointestinal motility which may be altered during obesity. This study compared the in vitro response and role of amino acid (AA) taste receptors (TASR) in the effect of AAs and a casein hydrolysate on ghrelin release and smooth muscle (SM) contractions in the proximal gut of lean and obese patients.status: publishe
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