Optic Nerve Hypoplasia Is a Pervasive Subcortical Pathology of Visual System in Neonates
- Liang, Chen
- Kerr, Alicia
- Qiu, Yangfengzhong
- Cristofoli, Francesca
- Van Esch, Hilde
- Fox, Michael A
- Mukherjee, Konark
Publication date
October 2017
DOI Publisher
Association for Research in Vision and Ophthalmology (ARVO) Journal
Investigative Ophthalmology & Visual ScienceAbstract
Optic nerve hypoplasia (ONH) is the most common cause of childhood congenital blindness in developed nations, yet the fundamental pathobiology of ONH remains unknown. The objective of this study was to employ a 'face validated' murine model to determine the timing of onset and the pathologic characteristics of ONH.status: publishe
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