This study evaluated tumor response to olaratumab (an anti-PDGFRα monoclonal antibody) in previously treated patients with metastatic gastrointestinal stromal tumor (GIST) with or without PDGFRα mutations (cohorts 1 and 2, respectively).status: publishe
Gastrointestinal stromal tumor (GIST) is a devastating disease, especially in the setting of metasta...
Item does not contain fulltextPURPOSE: Patients, platelet-derived growth factor receptor alpha (PDGF...
BACKGROUND: Soft tissue sarcoma (STS) comprises a family of rare, heterogeneous tumors of mesenchyma...
PURPOSE: The platelet-derived growth factor receptor (PDGFR) has an important role in tumorigenesis ...
Purpose: Platelet-derived growth factor receptor-alpha (PDGFRA) mutations are found in approximately...
Purpose: Platelet-derived growth factor receptor-alpha (PDGFRA) mutations are found in approximately...
PURPOSE: Platelet-derived growth factor receptor-alpha (PDGFRA) mutations are found in approximately...
International audiencePurpose: Platelet-derived growth factor receptor-alpha (PDGFRA) mutations are ...
PURPOSE: PDGFRA mutations are found in approximately 5-7% of advanced GIST. We sought to extensively...
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the strointestinal...
PURPOSE: Gastrointestinal stromal tumor (GIST) is a common type of soft-tissue sarcoma. Imatinib, an...
Gastrointestinal stromal tumors (GIST) are the most frequent mesenchymal tumors in the digestive tra...
This phase Ib study enumerated whole blood circulating tumor cells (CTC) and evaluated biomarkers in...
Most gastrointestinal stromal tumors (GISTs) are caused by oncogenic KIT or PDGFRA activation, and t...
Importance: After identification of activating mutations of the KIT gene in gastrointestinal stromal...
Gastrointestinal stromal tumor (GIST) is a devastating disease, especially in the setting of metasta...
Item does not contain fulltextPURPOSE: Patients, platelet-derived growth factor receptor alpha (PDGF...
BACKGROUND: Soft tissue sarcoma (STS) comprises a family of rare, heterogeneous tumors of mesenchyma...
PURPOSE: The platelet-derived growth factor receptor (PDGFR) has an important role in tumorigenesis ...
Purpose: Platelet-derived growth factor receptor-alpha (PDGFRA) mutations are found in approximately...
Purpose: Platelet-derived growth factor receptor-alpha (PDGFRA) mutations are found in approximately...
PURPOSE: Platelet-derived growth factor receptor-alpha (PDGFRA) mutations are found in approximately...
International audiencePurpose: Platelet-derived growth factor receptor-alpha (PDGFRA) mutations are ...
PURPOSE: PDGFRA mutations are found in approximately 5-7% of advanced GIST. We sought to extensively...
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the strointestinal...
PURPOSE: Gastrointestinal stromal tumor (GIST) is a common type of soft-tissue sarcoma. Imatinib, an...
Gastrointestinal stromal tumors (GIST) are the most frequent mesenchymal tumors in the digestive tra...
This phase Ib study enumerated whole blood circulating tumor cells (CTC) and evaluated biomarkers in...
Most gastrointestinal stromal tumors (GISTs) are caused by oncogenic KIT or PDGFRA activation, and t...
Importance: After identification of activating mutations of the KIT gene in gastrointestinal stromal...
Gastrointestinal stromal tumor (GIST) is a devastating disease, especially in the setting of metasta...
Item does not contain fulltextPURPOSE: Patients, platelet-derived growth factor receptor alpha (PDGF...
BACKGROUND: Soft tissue sarcoma (STS) comprises a family of rare, heterogeneous tumors of mesenchyma...