A Genetic Variation in the Neonatal Fc-Receptor Affects Anti-TNF Drug Concentrations in Inflammatory Bowel Disease

Cytokine gene polymorphisms in inflammatory bowel disease.

Louis, Edouard
Satsangi, J.
Roussomoustakaki, M.
Parkes, M.
Fanning, G.
Welsh, K.
Jewell, D.

January 1996

BACKGROUND: Concordance rates in siblings and twins provide strong evidence that genetic susceptibil...

Toll-like receptor-1,-2, and-6 polymorphisms influence disease extension in inflammatory bowel diseases

Pierik, M
Joossens, S
Van Steen, Kristel
Van Schuerbeek, N
Vlietinck, R
Rutgeerts, P
Vermeire, S

January 2006

Background: Evidence that a deficient innate immune response toward the bacterial flora of the gut p...

Farnesoid X receptor (FXR) activation and FXR genetic variation in inflammatory bowel disease.

Nijmeijer, Rian M
Gadaleta, Raffaella M
van Mil, Saskia WC
van Bodegraven, Adriaan A
Crusius, J Bart A
Dijkstra, Gerard
Hommes, Daan W
de Jong, Dirk J
Stokkers, Pieter CF
Verspaget, Hein W
Weersma, Rinse K
van der Woude, C Janneke
Stapelbroek, Janneke M
Schipper, Marguerite EI
Wijmenga, Cisca
van Erpecum, Karel J
Oldenburg, Bas
Dutch Initiative on Crohn, Colitis (ICC)

January 2011

BackgroundWe previously showed that activation of the bile salt nuclear receptor Farnesoid X Recepto...

A Genetic Variation in the Neonatal Fc-Receptor Affects Anti-TNF Drug Concentrations in Inflammatory Bowel Disease

Billiet, Thomas
Dreesen, Erwin
Cleynen, Isabelle
Wollants, Willem-Jan
Ferrante, Marc
Van Assche, Gert
Gils, Ann
Vermeire, Séverine

October 2016

Ample evidence exists that Anti-tumor necrosis factor (TNF) concentrations during induction determin...

Farnesoid X receptor (FXR) activation and FXR genetic variation in inflammatory bowel disease

Nijmeijer, Rian
Gadaleta, Raffaella
Mil, Saskia
Bodegraven, Ad
Crusius, Bart
Dijkstra, Gerard
Hommes, Daniël
Jong, Dirk
Stokkers, Pieter
Verspaget, Hein
Weersma, Rinse
Woude, Janneke
Stapelbroek, Janneke
Schipper, Marguerite
Wijmenga, Cisca
Erpecum, Karel
Oldenburg, Bas

August 2011

textabstractBackground: We previously showed that activation of the bile salt nuclear receptor Farne...

Farnesoid X Receptor (FXR) Activation and FXR Genetic Variation in Inflammatory Bowel Disease

Nijmeijer, RM
Gadaleta, RM
van Mil, SWC
van Bodegraven, AA
Crusius, JBA
Dijkstra, GJJ (Gerard)
Hommes, DW
de Jong, DJ
Stokkers, PCF
Verspaget, HW
Weersma, RK
van der Woude, C.J.
Stapelbroek, JM
Schipper, Marguérite
Wijmenga, C
van Erpecum, KJ
Oldenburg, B

January 2011

Background: We previously showed that activation of the bile salt nuclear receptor Farnesoid X Recep...

Association of FcgR2a, but not FcgR3a, with inflammatory bowel diseases across three Caucasian populations.

Weersma, R.K.
Crusius, J.B.
Roberts, R.L.
Koeleman, B.P.
Palomino-Morales, R.
Wolfkamp, S.
Hollis-Moffatt, J.E.
Festen, E.A.
Meisneris, S.
Heijmans, R.
Noble, C.L.
Gearry, R.B.
Barclay, M.L.
Gomez-Garcia, M.
Lopez-Nevot, M.A.
Nieto, A.
Rodrigo, L.
Radstake, T.R.D.J.
Bodegraven, A.A. van
Wijmenga, C.
Merriman, T.R.
Stokkers, P.C.
Pena, A.S.
Martin, J.
Alizadeh, B.Z.

January 2010

Item does not contain fulltextBACKGROUND: The Fc receptors II and III (FcgR2a, and FcgR3a) play a cr...

Sixteen functional single nucleotide polymorphisms (SNPs) in 13 genes involved in regulation of inflammation were found to be associated with susceptability of severe Crohn's disease (CD), ulcerative colitis (UC) or inflammatory bowel diseases (IBD).

Steffen Bank (589032)
Paal Skytt Andersen (331783)
Johan Burisch (590117)
Natalia Pedersen (590118)
Stine Roug (590119)
Julie Galsgaard (590120)
Stine Ydegaard Turino (590121)
Jacob Broder Brodersen (590122)
Shaista Rashid (590123)
Britt Kaiser Rasmussen (590124)
Sara Avlund (590125)
Thomas Bastholm Olesen (590126)
Hans Jürgen Hoffmann (590127)
Marianne Kragh Thomsen (589033)
Vibeke Østergaard Thomsen (547738)
Morten Frydenberg (346317)
Bjørn Andersen Nexø (21238)
Jacob Sode (589031)
Ulla Vogel (21241)
Vibeke Andersen (447795)

June 2014

<p>Eleven of the SNPs have not previously been reported as susceptability polymorphisms of CD, UC or...

Association of FcgR2a, but Not FcgR3a, with Inflammatory Bowel Diseases Across Three Caucasian Populations

Weersma, Rinse K.
Crusius, J. Bart A.
Roberts, Rebecca L.
Koeleman, Bobby P. C.
Palomino-Morales, Rogelio
Wolfkamp, Simone
Hollis-Moffatt, Jade E.
Festen, Eleonora A. M.
Meisneris, Sander
Heijmans, Roel
Noble, Colin L.
Gearry, Richard B.
Barclay, Murrary L.
Gomez-Garcia, Maria
Lopez-Nevot, Miguel A.
Nieto, Antonio
Rodrigo, Luis
Radstake, Timothy R. D. J.
van Bodegraven, Adriaan A.
Wijmenga, Cisca
Merriman, Tony R.
Stokkers, Pieter C. F.
Pena, A. Salvador
Martin, Javier
Alizadeh, Behrooz Z.

December 2010

Background: The Fc receptors II and III (FcgR2a, and FcgR3a) play a crucial role in the regulation o...

Polymorphism of TNF-alfa but not MDR-1 influence response to medical therapy in pediatric onset inflammatory bowel disease. (I.F. 2.102)

S. CUCCHIARA
A. LATIANO
O. PALMIERI
R. BERNI CANANI
R. D'INCÀ
G. GUARISO
G. VIENI
D. DE VUNUTO
G. RIEGLER
D. GUAGNOZZI
C. BASCIETTO
E. MIELE
M. R. VALVANO
F. BOSSA
V. ANNESE
DE ANGELIS, Gian Luigi

January 2007

Aim: We investigated the contribution of variants of tumour necrosis factor (TNF)-a and MDR1 genes ...

The role of the Toll receptor pathway in susceptibility to inflammatory bowel diseases

De Jager, PL
Franchimont, D
Waliszewska, A
Bitton, A
Cohen, A
Langelier, D
Belaiche, J
Vermeire, Severine
Farwell, L
Goris, An
Libioulle, C
Jani, N
Dassopoulos, T
Bromfield, GP
Dubois, Bénédicte
Cho, JH
Brant, SR
Duerr, RH
Yang, Hu
Rotter, JI
Silverberg, MS
Steinhart, AH
Daly, MJ
Podolsky, DK
Louis, E
Hafler, DA
Rioux, JD

July 2007

The intestinal flora has long been thought to play a role either in initiating or in exacerbating th...

Association between genotypes of rs34436714 of NLRP12 and serum tumor necrosis factor-alpha in inflammatory bowel disease: A case-control study

Dellaporta, E.
Lazaridis, L.D.
Koussoulas, V.
Netea, M.G.
Giamarellos-Bourboulis, E.J.
Triantafyllou, K.

January 2019

We aimed to investigate the impact of the single nucleotide polymorphisms of rs34436714 of the NOD-l...

Variations in inflammatory genes as molecular markers for prediction of inflammatory bowel disease occurrence

Stanković, Biljana
Dragasević, Sanja
Popović, Dragan
Zukić, Branka
Kotur, Nikola
Sokić-Milutinović, Aleksandra
Alempijević, Tamara
Lukić, Snežana
Milosavljević, Tomica
Nikčević, Gordana
Pavlović, Sonja

January 2015

OBJECTIVE: Research on inflammatory bowel disease (IBD) has highlighted genes involved in the regula...

Polymorphisms of tumor necrosis factor-alpha but not MDR1 influence response to medical therapy in pediatric-onset inflammatory bowel disease

Cucchiara, S
Latiano, A
Palmieri, O
Canani, Rb
D'Inca', R
Guariso, Graziella
Vieni, G
DE VENUTO, D
Riegler, G
De'Angelis, Gl
Guagnozzi, D
Bascietto, C
Miele, E
Valvano, Mr
Bossa, F
Annese, V.

January 2007

Abstract AIM: We investigated the contribution of variants of tumour necrosis factor (TNF)-alpha an...

Polymorphisms of TNF-alpha but not MDR-1influence response to medical therapy in pediatric onset inflammatory bowel disease

CUCCHIARA S
LATIANO A
PALMIERI O
BERNI CANANI, ROBERTO
DINC R
GUARISO G
VIENI G
DE VENUTO D
RIEGLER G
DEANGELIS GL
GUAGNOZZI D
BASCIETTO C
MIELE, ERASMO
MALVANO M. R
BOSSA F
ANNESE V.

January 2007

AIM: We investigated the contribution of variants of tumour necrosis factor (TNF)-alpha and MDR1 ge...

Cytokine gene polymorphisms in inflammatory bowel disease.

Louis, Edouard
Satsangi, J.
Roussomoustakaki, M.
Parkes, M.
Fanning, G.
Welsh, K.
Jewell, D.

January 1996

BACKGROUND: Concordance rates in siblings and twins provide strong evidence that genetic susceptibil...

Toll-like receptor-1,-2, and-6 polymorphisms influence disease extension in inflammatory bowel diseases

Pierik, M
Joossens, S
Van Steen, Kristel
Van Schuerbeek, N
Vlietinck, R
Rutgeerts, P
Vermeire, S

January 2006

Background: Evidence that a deficient innate immune response toward the bacterial flora of the gut p...

Farnesoid X receptor (FXR) activation and FXR genetic variation in inflammatory bowel disease.

Nijmeijer, Rian M
Gadaleta, Raffaella M
van Mil, Saskia WC
van Bodegraven, Adriaan A
Crusius, J Bart A
Dijkstra, Gerard
Hommes, Daan W
de Jong, Dirk J
Stokkers, Pieter CF
Verspaget, Hein W
Weersma, Rinse K
van der Woude, C Janneke
Stapelbroek, Janneke M
Schipper, Marguerite EI
Wijmenga, Cisca
van Erpecum, Karel J
Oldenburg, Bas
Dutch Initiative on Crohn, Colitis (ICC)

January 2011

BackgroundWe previously showed that activation of the bile salt nuclear receptor Farnesoid X Recepto...

A Genetic Variation in the Neonatal Fc-Receptor Affects Anti-TNF Drug Concentrations in Inflammatory Bowel Disease

Billiet, Thomas
Dreesen, Erwin
Cleynen, Isabelle
Wollants, Willem-Jan
Ferrante, Marc
Van Assche, Gert
Gils, Ann
Vermeire, Séverine

October 2016

Ample evidence exists that Anti-tumor necrosis factor (TNF) concentrations during induction determin...

Farnesoid X receptor (FXR) activation and FXR genetic variation in inflammatory bowel disease

Nijmeijer, Rian
Gadaleta, Raffaella
Mil, Saskia
Bodegraven, Ad
Crusius, Bart
Dijkstra, Gerard
Hommes, Daniël
Jong, Dirk
Stokkers, Pieter
Verspaget, Hein
Weersma, Rinse
Woude, Janneke
Stapelbroek, Janneke
Schipper, Marguerite
Wijmenga, Cisca
Erpecum, Karel
Oldenburg, Bas

August 2011

textabstractBackground: We previously showed that activation of the bile salt nuclear receptor Farne...

Farnesoid X Receptor (FXR) Activation and FXR Genetic Variation in Inflammatory Bowel Disease

Nijmeijer, RM
Gadaleta, RM
van Mil, SWC
van Bodegraven, AA
Crusius, JBA
Dijkstra, GJJ (Gerard)
Hommes, DW
de Jong, DJ
Stokkers, PCF
Verspaget, HW
Weersma, RK
van der Woude, C.J.
Stapelbroek, JM
Schipper, Marguérite
Wijmenga, C
van Erpecum, KJ
Oldenburg, B

January 2011

Background: We previously showed that activation of the bile salt nuclear receptor Farnesoid X Recep...

Association of FcgR2a, but not FcgR3a, with inflammatory bowel diseases across three Caucasian populations.

Weersma, R.K.
Crusius, J.B.
Roberts, R.L.
Koeleman, B.P.
Palomino-Morales, R.
Wolfkamp, S.
Hollis-Moffatt, J.E.
Festen, E.A.
Meisneris, S.
Heijmans, R.
Noble, C.L.
Gearry, R.B.
Barclay, M.L.
Gomez-Garcia, M.
Lopez-Nevot, M.A.
Nieto, A.
Rodrigo, L.
Radstake, T.R.D.J.
Bodegraven, A.A. van
Wijmenga, C.
Merriman, T.R.
Stokkers, P.C.
Pena, A.S.
Martin, J.
Alizadeh, B.Z.

January 2010

Item does not contain fulltextBACKGROUND: The Fc receptors II and III (FcgR2a, and FcgR3a) play a cr...

Sixteen functional single nucleotide polymorphisms (SNPs) in 13 genes involved in regulation of inflammation were found to be associated with susceptability of severe Crohn's disease (CD), ulcerative colitis (UC) or inflammatory bowel diseases (IBD).

Steffen Bank (589032)
Paal Skytt Andersen (331783)
Johan Burisch (590117)
Natalia Pedersen (590118)
Stine Roug (590119)
Julie Galsgaard (590120)
Stine Ydegaard Turino (590121)
Jacob Broder Brodersen (590122)
Shaista Rashid (590123)
Britt Kaiser Rasmussen (590124)
Sara Avlund (590125)
Thomas Bastholm Olesen (590126)
Hans Jürgen Hoffmann (590127)
Marianne Kragh Thomsen (589033)
Vibeke Østergaard Thomsen (547738)
Morten Frydenberg (346317)
Bjørn Andersen Nexø (21238)
Jacob Sode (589031)
Ulla Vogel (21241)
Vibeke Andersen (447795)

June 2014

<p>Eleven of the SNPs have not previously been reported as susceptability polymorphisms of CD, UC or...

Association of FcgR2a, but Not FcgR3a, with Inflammatory Bowel Diseases Across Three Caucasian Populations

Weersma, Rinse K.
Crusius, J. Bart A.
Roberts, Rebecca L.
Koeleman, Bobby P. C.
Palomino-Morales, Rogelio
Wolfkamp, Simone
Hollis-Moffatt, Jade E.
Festen, Eleonora A. M.
Meisneris, Sander
Heijmans, Roel
Noble, Colin L.
Gearry, Richard B.
Barclay, Murrary L.
Gomez-Garcia, Maria
Lopez-Nevot, Miguel A.
Nieto, Antonio
Rodrigo, Luis
Radstake, Timothy R. D. J.
van Bodegraven, Adriaan A.
Wijmenga, Cisca
Merriman, Tony R.
Stokkers, Pieter C. F.
Pena, A. Salvador
Martin, Javier
Alizadeh, Behrooz Z.

December 2010

Background: The Fc receptors II and III (FcgR2a, and FcgR3a) play a crucial role in the regulation o...

Polymorphism of TNF-alfa but not MDR-1 influence response to medical therapy in pediatric onset inflammatory bowel disease. (I.F. 2.102)

S. CUCCHIARA
A. LATIANO
O. PALMIERI
R. BERNI CANANI
R. D'INCÀ
G. GUARISO
G. VIENI
D. DE VUNUTO
G. RIEGLER
D. GUAGNOZZI
C. BASCIETTO
E. MIELE
M. R. VALVANO
F. BOSSA
V. ANNESE
DE ANGELIS, Gian Luigi

January 2007

Aim: We investigated the contribution of variants of tumour necrosis factor (TNF)-a and MDR1 genes ...

The role of the Toll receptor pathway in susceptibility to inflammatory bowel diseases

De Jager, PL
Franchimont, D
Waliszewska, A
Bitton, A
Cohen, A
Langelier, D
Belaiche, J
Vermeire, Severine
Farwell, L
Goris, An
Libioulle, C
Jani, N
Dassopoulos, T
Bromfield, GP
Dubois, Bénédicte
Cho, JH
Brant, SR
Duerr, RH
Yang, Hu
Rotter, JI
Silverberg, MS
Steinhart, AH
Daly, MJ
Podolsky, DK
Louis, E
Hafler, DA
Rioux, JD

July 2007

The intestinal flora has long been thought to play a role either in initiating or in exacerbating th...

Association between genotypes of rs34436714 of NLRP12 and serum tumor necrosis factor-alpha in inflammatory bowel disease: A case-control study

Dellaporta, E.
Lazaridis, L.D.
Koussoulas, V.
Netea, M.G.
Giamarellos-Bourboulis, E.J.
Triantafyllou, K.

January 2019

We aimed to investigate the impact of the single nucleotide polymorphisms of rs34436714 of the NOD-l...

Variations in inflammatory genes as molecular markers for prediction of inflammatory bowel disease occurrence

Stanković, Biljana
Dragasević, Sanja
Popović, Dragan
Zukić, Branka
Kotur, Nikola
Sokić-Milutinović, Aleksandra
Alempijević, Tamara
Lukić, Snežana
Milosavljević, Tomica
Nikčević, Gordana
Pavlović, Sonja

January 2015

OBJECTIVE: Research on inflammatory bowel disease (IBD) has highlighted genes involved in the regula...

Polymorphisms of tumor necrosis factor-alpha but not MDR1 influence response to medical therapy in pediatric-onset inflammatory bowel disease

Cucchiara, S
Latiano, A
Palmieri, O
Canani, Rb
D'Inca', R
Guariso, Graziella
Vieni, G
DE VENUTO, D
Riegler, G
De'Angelis, Gl
Guagnozzi, D
Bascietto, C
Miele, E
Valvano, Mr
Bossa, F
Annese, V.

January 2007

Abstract AIM: We investigated the contribution of variants of tumour necrosis factor (TNF)-alpha an...

Polymorphisms of TNF-alpha but not MDR-1influence response to medical therapy in pediatric onset inflammatory bowel disease

CUCCHIARA S
LATIANO A
PALMIERI O
BERNI CANANI, ROBERTO
DINC R
GUARISO G
VIENI G
DE VENUTO D
RIEGLER G
DEANGELIS GL
GUAGNOZZI D
BASCIETTO C
MIELE, ERASMO
MALVANO M. R
BOSSA F
ANNESE V.

January 2007

AIM: We investigated the contribution of variants of tumour necrosis factor (TNF)-alpha and MDR1 ge...

Cytokine gene polymorphisms in inflammatory bowel disease.

Louis, Edouard
Satsangi, J.
Roussomoustakaki, M.
Parkes, M.
Fanning, G.
Welsh, K.
Jewell, D.

January 1996

BACKGROUND: Concordance rates in siblings and twins provide strong evidence that genetic susceptibil...

Toll-like receptor-1,-2, and-6 polymorphisms influence disease extension in inflammatory bowel diseases

Pierik, M
Joossens, S
Van Steen, Kristel
Van Schuerbeek, N
Vlietinck, R
Rutgeerts, P
Vermeire, S

January 2006

Background: Evidence that a deficient innate immune response toward the bacterial flora of the gut p...

Farnesoid X receptor (FXR) activation and FXR genetic variation in inflammatory bowel disease.

Nijmeijer, Rian M
Gadaleta, Raffaella M
van Mil, Saskia WC
van Bodegraven, Adriaan A
Crusius, J Bart A
Dijkstra, Gerard
Hommes, Daan W
de Jong, Dirk J
Stokkers, Pieter CF
Verspaget, Hein W
Weersma, Rinse K
van der Woude, C Janneke
Stapelbroek, Janneke M
Schipper, Marguerite EI
Wijmenga, Cisca
van Erpecum, Karel J
Oldenburg, Bas
Dutch Initiative on Crohn, Colitis (ICC)

January 2011

BackgroundWe previously showed that activation of the bile salt nuclear receptor Farnesoid X Recepto...

A Genetic Variation in the Neonatal Fc-Receptor Affects Anti-TNF Drug Concentrations in Inflammatory Bowel Disease

Abstract

Extracted data

A Genetic Variation in the Neonatal Fc-Receptor Affects Anti-TNF Drug Concentrations in Inflammatory Bowel Disease

Abstract

Extracted data

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