Cardiomyopathy is among the leading causes of death from systemic sclerosis (SSc). Urokinase-type plasminogen activator receptor (uPAR)-deficient mice have been recently reported to display important histopathological hallmarks of SSc, including dermal fibrosis, reduced dermal capillary density, and pulmonary fibrosis. Here, we investigated whether uPAR-deficient mice could display the histopathological features of SSc-related cardiomyopathy.status: publishe
Atherosclerosis, a chronic inflammatory disease, arises from metabolic disorders and is driven by in...
BACKGROUND: Chronic hypoxia results in the development of pulmonary hypertension and subsequent righ...
Background. Systemic sclerosis (SSc) is an autoimmune disease characterized by excessive fibrosis in...
Cardiomyopathy is among the leading causes of death from systemic sclerosis (SSc). Urokinase-type pl...
Urokinase-type plasminogen activator receptor (uPAR) is a key component of the fibrinolytic system i...
The study of the mechanisms of development and progression of fibrosis is one of the key directions ...
The fibrinolytic system is considered to play an important role in the degradation of extracellular ...
Urokinase plasminogen activator (uPA) is strongly expressed in atherosclerotic lesions, but the over...
Atherosclerosis, a chronic inflammatory disease, arises from metabolic disorders and is driven by in...
Systemic sclerosis (SSc) is characterized by excessive fibrosis throughout the body. There are two m...
Duchenne muscular dystrophy (l is a fatal and incurable muscle degenerative disorder. We identify a ...
RATIONALE: Up to 10% of patients with systemic sclerosis (SSc) develop pulmonary arterial hypertensi...
Background. Systemic sclerosis (SSc) is an autoimmune disease characterized by excessive fibrosis in...
OBJECTIVE—Absence of stearoyl-CoA desaturase-1 (SCD1) in mice reduces plasma triglycerides and provi...
Objective—The urokinase-type plasminogen activator (uPA) and its specific receptor (uPAR) are a pote...
Atherosclerosis, a chronic inflammatory disease, arises from metabolic disorders and is driven by in...
BACKGROUND: Chronic hypoxia results in the development of pulmonary hypertension and subsequent righ...
Background. Systemic sclerosis (SSc) is an autoimmune disease characterized by excessive fibrosis in...
Cardiomyopathy is among the leading causes of death from systemic sclerosis (SSc). Urokinase-type pl...
Urokinase-type plasminogen activator receptor (uPAR) is a key component of the fibrinolytic system i...
The study of the mechanisms of development and progression of fibrosis is one of the key directions ...
The fibrinolytic system is considered to play an important role in the degradation of extracellular ...
Urokinase plasminogen activator (uPA) is strongly expressed in atherosclerotic lesions, but the over...
Atherosclerosis, a chronic inflammatory disease, arises from metabolic disorders and is driven by in...
Systemic sclerosis (SSc) is characterized by excessive fibrosis throughout the body. There are two m...
Duchenne muscular dystrophy (l is a fatal and incurable muscle degenerative disorder. We identify a ...
RATIONALE: Up to 10% of patients with systemic sclerosis (SSc) develop pulmonary arterial hypertensi...
Background. Systemic sclerosis (SSc) is an autoimmune disease characterized by excessive fibrosis in...
OBJECTIVE—Absence of stearoyl-CoA desaturase-1 (SCD1) in mice reduces plasma triglycerides and provi...
Objective—The urokinase-type plasminogen activator (uPA) and its specific receptor (uPAR) are a pote...
Atherosclerosis, a chronic inflammatory disease, arises from metabolic disorders and is driven by in...
BACKGROUND: Chronic hypoxia results in the development of pulmonary hypertension and subsequent righ...
Background. Systemic sclerosis (SSc) is an autoimmune disease characterized by excessive fibrosis in...