The Role of LOX and LOXL2 in the Pathogenesis of an Experimental Model of Choroidal Neovascularization
- Van Bergen, Tine
- Spangler, Rhyannon
- Marshall, Derek
- Hollanders, Karolien
- Van de Veire, Sara
- Vandewalle, Evelien
- Moons, Lieve
- Herman, Jean
- Smith, Victoria
- Stalmans, Ingeborg
Publication date
August 2015
DOI Publisher
Association for Research in Vision and Ophthalmology (ARVO) Journal
Investigative Ophthalmology & Visual ScienceAbstract
We investigated whether lysyl oxidase (LOX) and lysyl oxidase-like 2 (LOXL2) play a role in an experimental model of choroidal neovascularization (CNV). The therapeutic potential of antibodies against LOX (M64) and LOXL2 (AB0023) was evaluated in a murine laser-induced CNV model.status: publishe
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