COMT Val158Met moderation of stress-induced psychosis
- Stefanis, Nicholas C
- Henquet, Cécile
- Avramopoulos, Dimitrios
- Smyrnis, Nikolaos
- Evdokimidis, Ioannis
- Myin-Germeys, Inez
- Stefanis, Costas N
- Van Os, Jim
Publication date
November 2007
DOI Publisher
Cambridge University Press (CUP) Journal
Psychological MedicineAbstract
Exposure to stressful life events increases the risk of developing a psychotic disorder. Moreover, increased reactivity to stress seems to represent part of the vulnerability for psychosis. This study aimed to investigate whether a functional polymorphism in the catechol-O-methyltransferase (COMT Val(158)Met) gene moderates the psychosis-inducing effects of stress.status: publishe
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