Longitudinal genetic characterization reveals that Cell Proliferation Maintains a Persistent HIV Type 1 DNA Pool During Effective HIV Therapy
- von Stockenstrom, Susanne
- Odevall, Lina
- Lee, Eunok
- Sinclair, Elizabeth
- Bacchetti, Peter
- Killian, Maudi
- Epling, Lorrie
- Shao, Wei
- Hoh, Rebecca
- Ho, Terence
- Faria, Nuno R
- Lemey, Philippe
- Albert, Jan
- Hunt, Peter
- Loeb, Lisa
- Pilcher, Christopher
- Poole, Lauren
- Hatano, Hiroyu
- Somsouk, Ma
- Douek, Daniel
- Boritz, Eli
- Deeks, Steven G
- Hecht, Frederick M
- Palmer, Sarah
Publication date
August 2015
DOI Publisher
Oxford University Press (OUP) Journal
The Journal of Infectious DiseasesAbstract
The stability of the human immunodeficiency virus type 1 (HIV-1) reservoir and the contribution of cellular proliferation to the maintenance of the reservoir during treatment are uncertain. Therefore, we conducted a longitudinal analysis of HIV-1 in T-cell subsets in different tissue compartments from subjects receiving effective antiretroviral therapy (ART).status: publishe
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