Cytokines in systemic juvenile idiopathic arthritis and haemophagocytic lymphohistiocytosis: tipping the balance between interleukin-18 and interferon-γ

Interleukin 18 as a marker of disease activity and severity in patients with juvenile idiopathic arthritis

Lotito, Ana Paola N.
Campa, Ana
Silva, Clovis A. A.
Kiss, Maria H. B.
Mello, Suzana B. V.

April 2007

Objective. To verify the importance of interleukin 18 (IL-18) in the pathogenesis of juvenile idiopa...

Distinct cytokine profiles of systemic-onset juvenile idiopathic arthritis-associated macrophage activation syndrome with particular emphasis on the role of interleukin-18 in its pathogenesis

Shimizu Masaki
Yokoyama Tadafumi
Yamada Keiko
Kaneda Hisashi
Wada Hideo
Wada Taizo
Toma Tomoko
Ohta Kazuhide
Kasahara Yoshihito
Yachie Akihiro

May 2010

Objectives: To compare the pro-inflammatory cytokine profiles and the cytokine kinetics in patients ...

IL-18 as a biomarker linking systemic juvenile idiopathic arthritis and macrophage activation syndrome

Yasin, Shima
Fall, Ndate
Brown, Rachel A
Henderlight, Maggie
Canna, Scott W
Girard, Charlotte
Gabay, Cem
Grom, Alexei A
Schulert, Grant S

January 2020

Systemic juvenile idiopathic arthritis (sJIA) is a childhood arthritis with features of autoinflamma...

Cytokines in systemic juvenile idiopathic arthritis and haemophagocytic lymphohistiocytosis: tipping the balance between interleukin-18 and interferon-γ

Put, Karen
Avau, Anneleen
Brisse, Ellen
Mitera, Tania
Put, Stéphanie
Proost, Paul
Bader-Meunier, Brigitte
Westhovens, René
Van den Eynde, Benoit J
Orabona, Ciriana
Fallarino, Francesca
De Somer, Lien
Tousseyn, Thomas
Quartier, Pierre
Wouters, Carine
Matthys, Patrick

August 2015

To study the role of IFN-γ in the pathogenesis of systemic JIA (sJIA) and haemophagocytic lymphohist...

Original article

Karen Put
Anneleen Avau
Ellen Brisse
Tania Mitera
Paul Proost
Brigitte Bader-meunier
Rene ́ Westhovens
Benoit J. Van Den Eynde
Ciriana Orabona
Francesca Fallarino
Lien De Somer Thomas Tousseyn
Patrick Matthys

September 2016

Cytokines in systemic juvenile idiopathic arthritis and haemophagocytic lymphohistiocytosis: tipping...

Potential Effects of Interleukins on the Pathogenesis of Systemic Onset Juvenile Idiopathic Arthritis

Xu, Ling-Yun
Zhang, Wen-Ming
Xia, Min
Cao, Lan-Fang

October 2016

BackgroundTo analyze the correlation of cytokines with clinical inflammatory indexes in systemic ons...

Interferon-gamma and natural killer cells in systemic juvenile idiopathic arthritis and macrophage activation syndrome

Put, Karen

October 2015

Systemic juvenile idiopathic arthritis (sJIA) is a severe childhood immune-inflammatory disorder cha...

Distinct expression pattern of IFN-α and TNF-α in juvenile idiopathic arthritis synovial tissue

Gattorno M.
Chicha L.
Gregorio A.
Ferlito F.
Rossi F.
Jarrossay D.
Lanzavecchia A.
Martini A.
Manz M. G.

January 2007

Objectives. Recent laboratory and clinical data suggest that two prototype autoimmune diseases, syst...

What do cytokine profiles tell us about subsets of juvenile idiopathic arthritis?

Cimaz, Rolando
Moretti, Davide
Pagnini, Ilaria
Marino, Achille
Simonini, Gabriele
CANTARINI, LUCA

January 2012

Classification of juvenile idiopathic arthritis is an ongoing process and up to now has been predomi...

Cytokine production by peripheral blood mononuclear cells from patients with juvenile idiopathic arthritis

Aggarwal, Amita
Mishra, R.

January 2002

Juvenile idiopathic arthritis (JIA) is a chronic inflammatory arthritis of childhood characterized b...

Interferon-gamma en 'natural killer' cellen in systemische juveniele idiopathische artritis en macrofaagactivatiesyndroom

Put, Karen

October 2015

Systemic juvenile idiopathic arthritis (sJIA) is a severe childhood immune-inflammatory disorder cha...

Extremely elevated IL-18 levels may help distinguish systemic-onset juvenile idiopathic arthritis from other febrile diseases

Y. Xia (704201)
P. Cui (2664604)
Q. Li (10854)
F. Liang (6509675)
C. Li (2717329)
J. Yang (1558195)

February 2017

The aim of this research was to explore whether IL-18 can be a serological marker for the diagnosis ...

Identification of cytokine cell sources in a new mouse model of systemic juvenile idiopathic arthritis highlights innate immunity of this disorder

Avau, Anneleen
Imbrechts, Maya
Put, Karen
Brisse, Ellen
Mitera, Tania
Leclercq, Georges
Wouters, Carine
Matthys, Patrick

November 2015

Objective Systemic juvenile idiopathic arthritis (sJIA) is a rheumatic childhood disease, with disti...

Elevated circulating levels of interferon-γ and interferon-γ-induced chemokines characterise patients with macrophage activation syndrome complicating systemic juvenile idiopathic arthritis

Bracaglia, Claudia
de Graaf, Kathy
Pires Marafon, Denise
Guilhot, Florence
Ferlin, Walter
Prencipe, Giusi
Caiello, Ivan
Davì, Sergio
Schulert, Grant
Ravelli, Angelo
Grom, Alexei A
de Min, Cristina
De Benedetti, Fabrizio

January 2017

Objectives Interferon-gamma (IFN gamma) is the pivotal mediator in murine models of primary haemopha...

Understanding inflammation in juvenile idiopathic arthritis : How immune biomarkers guide clinical strategies in the systemic onset subtype

Swart, JF
de Roock, Sytze
Prakken, Berent J

September 2016

The translation of basic insight in immunological mechanisms underlying inflammation into clinical p...

Interleukin 18 as a marker of disease activity and severity in patients with juvenile idiopathic arthritis

Lotito, Ana Paola N.
Campa, Ana
Silva, Clovis A. A.
Kiss, Maria H. B.
Mello, Suzana B. V.

April 2007

Objective. To verify the importance of interleukin 18 (IL-18) in the pathogenesis of juvenile idiopa...

Distinct cytokine profiles of systemic-onset juvenile idiopathic arthritis-associated macrophage activation syndrome with particular emphasis on the role of interleukin-18 in its pathogenesis

Shimizu Masaki
Yokoyama Tadafumi
Yamada Keiko
Kaneda Hisashi
Wada Hideo
Wada Taizo
Toma Tomoko
Ohta Kazuhide
Kasahara Yoshihito
Yachie Akihiro

May 2010

Objectives: To compare the pro-inflammatory cytokine profiles and the cytokine kinetics in patients ...

IL-18 as a biomarker linking systemic juvenile idiopathic arthritis and macrophage activation syndrome

Yasin, Shima
Fall, Ndate
Brown, Rachel A
Henderlight, Maggie
Canna, Scott W
Girard, Charlotte
Gabay, Cem
Grom, Alexei A
Schulert, Grant S

January 2020

Systemic juvenile idiopathic arthritis (sJIA) is a childhood arthritis with features of autoinflamma...

Cytokines in systemic juvenile idiopathic arthritis and haemophagocytic lymphohistiocytosis: tipping the balance between interleukin-18 and interferon-γ

Put, Karen
Avau, Anneleen
Brisse, Ellen
Mitera, Tania
Put, Stéphanie
Proost, Paul
Bader-Meunier, Brigitte
Westhovens, René
Van den Eynde, Benoit J
Orabona, Ciriana
Fallarino, Francesca
De Somer, Lien
Tousseyn, Thomas
Quartier, Pierre
Wouters, Carine
Matthys, Patrick

August 2015

To study the role of IFN-γ in the pathogenesis of systemic JIA (sJIA) and haemophagocytic lymphohist...

Original article

Karen Put
Anneleen Avau
Ellen Brisse
Tania Mitera
Paul Proost
Brigitte Bader-meunier
Rene ́ Westhovens
Benoit J. Van Den Eynde
Ciriana Orabona
Francesca Fallarino
Lien De Somer Thomas Tousseyn
Patrick Matthys

September 2016

Cytokines in systemic juvenile idiopathic arthritis and haemophagocytic lymphohistiocytosis: tipping...

Potential Effects of Interleukins on the Pathogenesis of Systemic Onset Juvenile Idiopathic Arthritis

Xu, Ling-Yun
Zhang, Wen-Ming
Xia, Min
Cao, Lan-Fang

October 2016

BackgroundTo analyze the correlation of cytokines with clinical inflammatory indexes in systemic ons...

Interferon-gamma and natural killer cells in systemic juvenile idiopathic arthritis and macrophage activation syndrome

Put, Karen

October 2015

Systemic juvenile idiopathic arthritis (sJIA) is a severe childhood immune-inflammatory disorder cha...

Distinct expression pattern of IFN-α and TNF-α in juvenile idiopathic arthritis synovial tissue

Gattorno M.
Chicha L.
Gregorio A.
Ferlito F.
Rossi F.
Jarrossay D.
Lanzavecchia A.
Martini A.
Manz M. G.

January 2007

Objectives. Recent laboratory and clinical data suggest that two prototype autoimmune diseases, syst...

What do cytokine profiles tell us about subsets of juvenile idiopathic arthritis?

Cimaz, Rolando
Moretti, Davide
Pagnini, Ilaria
Marino, Achille
Simonini, Gabriele
CANTARINI, LUCA

January 2012

Classification of juvenile idiopathic arthritis is an ongoing process and up to now has been predomi...

Cytokine production by peripheral blood mononuclear cells from patients with juvenile idiopathic arthritis

Aggarwal, Amita
Mishra, R.

January 2002

Juvenile idiopathic arthritis (JIA) is a chronic inflammatory arthritis of childhood characterized b...

Interferon-gamma en 'natural killer' cellen in systemische juveniele idiopathische artritis en macrofaagactivatiesyndroom

Put, Karen

October 2015

Systemic juvenile idiopathic arthritis (sJIA) is a severe childhood immune-inflammatory disorder cha...

Extremely elevated IL-18 levels may help distinguish systemic-onset juvenile idiopathic arthritis from other febrile diseases

Y. Xia (704201)
P. Cui (2664604)
Q. Li (10854)
F. Liang (6509675)
C. Li (2717329)
J. Yang (1558195)

February 2017

The aim of this research was to explore whether IL-18 can be a serological marker for the diagnosis ...

Identification of cytokine cell sources in a new mouse model of systemic juvenile idiopathic arthritis highlights innate immunity of this disorder

Avau, Anneleen
Imbrechts, Maya
Put, Karen
Brisse, Ellen
Mitera, Tania
Leclercq, Georges
Wouters, Carine
Matthys, Patrick

November 2015

Objective Systemic juvenile idiopathic arthritis (sJIA) is a rheumatic childhood disease, with disti...

Elevated circulating levels of interferon-γ and interferon-γ-induced chemokines characterise patients with macrophage activation syndrome complicating systemic juvenile idiopathic arthritis

Bracaglia, Claudia
de Graaf, Kathy
Pires Marafon, Denise
Guilhot, Florence
Ferlin, Walter
Prencipe, Giusi
Caiello, Ivan
Davì, Sergio
Schulert, Grant
Ravelli, Angelo
Grom, Alexei A
de Min, Cristina
De Benedetti, Fabrizio

January 2017

Objectives Interferon-gamma (IFN gamma) is the pivotal mediator in murine models of primary haemopha...

Understanding inflammation in juvenile idiopathic arthritis : How immune biomarkers guide clinical strategies in the systemic onset subtype

Swart, JF
de Roock, Sytze
Prakken, Berent J

September 2016

The translation of basic insight in immunological mechanisms underlying inflammation into clinical p...

Interleukin 18 as a marker of disease activity and severity in patients with juvenile idiopathic arthritis

Lotito, Ana Paola N.
Campa, Ana
Silva, Clovis A. A.
Kiss, Maria H. B.
Mello, Suzana B. V.

April 2007

Objective. To verify the importance of interleukin 18 (IL-18) in the pathogenesis of juvenile idiopa...

Distinct cytokine profiles of systemic-onset juvenile idiopathic arthritis-associated macrophage activation syndrome with particular emphasis on the role of interleukin-18 in its pathogenesis

Shimizu Masaki
Yokoyama Tadafumi
Yamada Keiko
Kaneda Hisashi
Wada Hideo
Wada Taizo
Toma Tomoko
Ohta Kazuhide
Kasahara Yoshihito
Yachie Akihiro

May 2010

Objectives: To compare the pro-inflammatory cytokine profiles and the cytokine kinetics in patients ...

IL-18 as a biomarker linking systemic juvenile idiopathic arthritis and macrophage activation syndrome

Yasin, Shima
Fall, Ndate
Brown, Rachel A
Henderlight, Maggie
Canna, Scott W
Girard, Charlotte
Gabay, Cem
Grom, Alexei A
Schulert, Grant S

January 2020

Systemic juvenile idiopathic arthritis (sJIA) is a childhood arthritis with features of autoinflamma...

Cytokines in systemic juvenile idiopathic arthritis and haemophagocytic lymphohistiocytosis: tipping the balance between interleukin-18 and interferon-γ

Abstract

Extracted data

Cytokines in systemic juvenile idiopathic arthritis and haemophagocytic lymphohistiocytosis: tipping the balance between interleukin-18 and interferon-γ

Abstract

Extracted data

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