Thresholds for conventional and home blood pressure by sex and age in 5018 participants from 5 populations
- Nomura, Kyoko
- Asayama, Kei
- Thijs, Lutgarde
- Niiranen, Teemu J
- Lujambio, Inés
- Boggia, José
- Hozawa, Atsushi
- Ohkubo, Takayoshi
- Hara, Azusa
- Johansson, Jouni K
- Sandoya, Edgardo
- Kollias, Anastasios
- Stergiou, George S
- Tsuji, Ichiro
- Jula, Antti M
- Imai, Yutaka
- Staessen, Jan A
- International Database of Home Blood Pressure in Relation to Cardiovascular Outcome Investigators
DOIAbstract
Whether blood pressure thresholds for hypertension should differ according to sex or age remains debated. We did a subject-level meta-analysis of 5018 people untreated for hypertension and randomly recruited from 5 populations (women, 56.7%; ≥60 years, 42.3%). We used multivariable-adjusted Cox regression and a bootstrap procedure to determine home blood pressure (HBP) levels yielding 10-year cardiovascular risks similar to those associated with established systolic/diastolic thresholds (140-160/80-100 mm Hg) for the conventional blood pressure (CBP). Conversely, we estimated CBP thresholds providing 10-year cardiovascular risks similar to those associated established HBP levels (125-135/80-85 mm Hg). All analyses were stratified for sex an...
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