Copyright © Melvin Bornstein, Joseph Lichtenberg, Donald Silver. Psychoanalysis is about asking the hard questions. This article applies this basic assumption of the clinical practice of psychoanalysis to the science of psychoanalysis. I focus on a number of key assumptions of psychoanalytic approaches and their epistemological status: (a) the theoretical language of psychoanalysis, (b) psychoanalytic technique and training, (c) psychoanalytic developmental theories, (d) object relational and attachment approaches within psychoanalysis, and (e) the nature of general explanatory models in psychoanalysis. These examples are far from exhaustive, but cover a broad set of historical and contemporary theoretical approaches within psychoanalysis. ...