The relationship between infliximab concentrations, antibodies to infliximab and disease activity in Crohn's disease
- Vande Casteele, Niels
- Khanna, Reena
- Levesque, Barrett G
- Stitt, Larry
- Zou, GY
- Singh, Sharat
- Lockton, Steve
- Hauenstein, Scott
- Ohrmund, Linda
- Greenberg, Gordon R
- Rutgeerts, Paul
- Gils, Ann
- Sandborn, William J
- Vermeire, Severine
- Feagan, Brian G
DOIAbstract
Although low infliximab trough concentrations and antibodies to infliximab (ATI) are associated with poor outcomes in patients with Crohn's disease (CD), the clinical relevance of ATI in patients with adequate infliximab concentrations is uncertain. We evaluated this question using an assay sensitive for identification of ATI in the presence of infliximab.status: publishe
Add to ORKG