Coffin-Siris and Nicolaides-Baraitser syndromes are a common well recognizable cause of intellectual disability

Nicolaides-Baraitser and Coffin-Siris syndromes are emerging conditions with overlapping clinical features including intellectual disability and typical somatic characteristics, especially sparse hair, low frontal hairline, large mouth with thick and everted lips, and hands and feet anomalies. Since 2012, mutations in genes encoding six proteins of the BAF complex were identified in both conditions.publisher: Elsevier articletitle: Coffin–Siris and Nicolaides–Baraitser syndromes are a common well recognizable cause of intellectual disability journaltitle: Brain and Development articlelink: http://dx.doi.org/10.1016/j.braindev.2014.08.009 content_type: article copyright: Copyright © 2014 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.status: publishe