Integration of proteomics, peptidomics and metabolomics in the hunt for diagnostic cancer markers in blood plasma

During tumor development potential markers, e.g. tumor-specific proteins, peptides and metabolic waste products, are secreted into the blood stream from the angiogenic switch onwards. Proteolytic fragments of proteins generated by tumor-specific proteases are released as well. Through a holistic omics approach, we are currently identifying and merging these secreted compounds in blood plasma. Validated cancer type specific markers will then be used in the development of a non-invasive, patient-friendly, reliable test for a highly sensitive and highly specific diagnosisstatus: publishe