The paper studies tension-tension fatigue behavior of a single-ply non-crimp 3D orthogonal weave E-glass composite and of a laminated composite reinforced with four plies of a standard plain weave fabric. Both composites have same total thickness and very close fiber volume fraction. The paper presents the description of the materials, the results of quasi-static tensile and of tension-tension fatigue tests, including the damage development during fatigue tensile loading. The non-crimp 3D woven fabric composite, loaded in both principal in-plane directions (warp and fill), shows the best quasi-static tensile properties and, when loaded in the fill direction, exhibits much longer fatigue life than its laminated plain weave counterpart. Durin...