Baseline characteristics of participants in the Hypertension in the Very Elderly Trial (HYVET)
- Bulpitt, CJ
- Beckett, NS
- Peters, R
- Banya, W
- Liu, L
- Wang, JG
- Stoyanovski, V
- Dumitrascu, D
- Nikitin, Y
- Staessen, Jan A
- Burch, L
- Fletcher, AE
DOIAbstract
The Hypertension in the Very Elderly Trial (HYVET) is a randomized double-blind trial of active antihypertensive treatment (indapamide 1.5 mg sustained release +/-2-4 mg perindopril) vs placebo in participants over the age of 80 years with a systolic blood pressure (SBP) of 160-199 mmHg during a placebo run-in period plus a diastolic blood pressure (DBP) of<110 mmHg. The trial has completed with 3845 subjects randomized and we report the baseline characteristics. The participants were a healthy group. The numbers smoking, drinking alcohol and having previous cardiovascular events were low, and their hypertensive status was not usually associated with the metabolic syndrome; 1.0% of the whole group had a total cholesterol over 8.0 mmol/l, 1....
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