In this issue of Cancer Cell, Dudley et al. (2008) report that endothelial cells (ECs) from murine prostate tumors unexpectedly differentiate into cells with characteristics of bone and cartilage and that human and murine prostate tumors contain "calcified" ECs. These observations open the possibility for targeted antiangiogenic therapy.status: publishe
Endothelial cells (ECs) play an important role in tumor progression. Currently, the main target of a...
The primary tumor microenvironment is inherently important in prostate cancer (PCa) initiation, grow...
Cooperation between endothelial cells and bone in bone remodelling is well established. In contrast,...
In this issue of Cancer Cell, Dudley et al. (2008) report that endothelial cells (ECs) from murine p...
SummarySolid tumors require new blood vessels for growth and metastasis, yet the biology of tumor-sp...
Prostate cancer cells metastasize to the bones, causing ectopic bone formation, which results in fra...
cancer, the disease metastasizes to bone and causes osteo-blastic growth. However, the mechanisms th...
Tumor metastasis is a highly inefficient biological process as millions of tumor cells are released ...
Emerging evidence indicates that the interactions between tumor cells and the bone microenvironment ...
Tumor progression depends on the process of angiogenesis, which is the formation of new blood vessel...
Cooperation between endothelial cells and bone in bone remodelling is well established. In contrast,...
he sustained growth of solid tumors requires the development of tumor-associated neovasculature for ...
BACKGROUND The underlying mechanisms permitting prostate cancer bone metastasis are poorly understo...
The primary tumor microenvironment is inherently important in prostate cancer (PCa) initiation, grow...
The growth of a malignant tumor beyond a certain, limited size requires that it first develop an ind...
Endothelial cells (ECs) play an important role in tumor progression. Currently, the main target of a...
The primary tumor microenvironment is inherently important in prostate cancer (PCa) initiation, grow...
Cooperation between endothelial cells and bone in bone remodelling is well established. In contrast,...
In this issue of Cancer Cell, Dudley et al. (2008) report that endothelial cells (ECs) from murine p...
SummarySolid tumors require new blood vessels for growth and metastasis, yet the biology of tumor-sp...
Prostate cancer cells metastasize to the bones, causing ectopic bone formation, which results in fra...
cancer, the disease metastasizes to bone and causes osteo-blastic growth. However, the mechanisms th...
Tumor metastasis is a highly inefficient biological process as millions of tumor cells are released ...
Emerging evidence indicates that the interactions between tumor cells and the bone microenvironment ...
Tumor progression depends on the process of angiogenesis, which is the formation of new blood vessel...
Cooperation between endothelial cells and bone in bone remodelling is well established. In contrast,...
he sustained growth of solid tumors requires the development of tumor-associated neovasculature for ...
BACKGROUND The underlying mechanisms permitting prostate cancer bone metastasis are poorly understo...
The primary tumor microenvironment is inherently important in prostate cancer (PCa) initiation, grow...
The growth of a malignant tumor beyond a certain, limited size requires that it first develop an ind...
Endothelial cells (ECs) play an important role in tumor progression. Currently, the main target of a...
The primary tumor microenvironment is inherently important in prostate cancer (PCa) initiation, grow...
Cooperation between endothelial cells and bone in bone remodelling is well established. In contrast,...
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