Some novel aminopropyl nucleoside phosphonates
- Zhou, Ding
- Lagoja, Irene M
- Van Aerschot, Arthur
Publication date
January 2007
DOI Publisher
Informa UK Limited Journal
Nucleosides Nucleotides & Nucleic AcidsAbstract
The aminopropyl nucleoside phosphonates 1-3 have an amino function within either the acyclic chain (series 2 and 3) or as substituent (series 1) of HPMPC (Cidofovir). Both purine and pyrimidine nucleoside anologs have been synthesized. In contrast to HPMPC, only a weak antiherpes virus activity could be demonstrated for 2b and 2c.status: publishe
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