Add to ORKGAn enantioselective approach towards the synthesis of optically pure cyclohexene nucleosides 3 has been developed starting from (R)-carvone. The key steps are the regio- and stereoselective hydroboration of an exo double bond, the selective reduction of an enone intermediate and introduction of a base moiety by Mitsunobu reaction. Conformational analysis showed that the adenine base adopts predominantly in a pseudo-axial position.status: publishe
Carbocyclic nucleosides (-)-5'-homocarbovir and (+)-epi-4'-homocarbovir were prepared from an acylni...
The enantioselective preparation of the two isomers of 4-hydroxy-2-cyclohexanone derivatives 1a,b wa...
(D)- and (L)-cyclohexeneyl-G were synthesized enantioselectively starting from (R)-carvone. Both sho...
3,5-dihydroxy-4-(hydroxymethyl)-1-cyclohexanyl adenine has been synthesized starting from (-)-carvon...
Enantioselective synthesis of a new family of unsaturated six-membered carbocyclic nucleosides using...
A stereoselective synthesis leading to (-)-ara-cyclohexenyl-adenine is described. The synthesis star...
Cyclohexenyl nucleosides (Figure 1) represent well-known biomimetic agents, working as bioactive nuc...
A cyclohexene ring has similar structural properties and conformational behavior to a saturated five...
With the aim to expand the repertoire of these bioactive nucleosides, we are currently exploring the...
The recent advances in the chemistry of carbocyclic nucleosides focused on different synthetic appro...
Racemic metyhl 3-cyclohexene-1-carboxylate was resolved via enzymatic hydrolysis to afford the enant...
A regio- and stereo-specific synthesis of cis-(±)-3-acetoxy-5- (acetoxymethyl)cyclopentene 3 from cy...
The cyclohexane nucleosides with a 1,4-relationship between nucleoside base and hydroxymethyl moiety...
Copyright © 2018, Georg Thieme Verlag. All rights reserved. We describe a short and stereospecific s...
with the aim to expand the repertoire of bioactive cyclohexenyl nucleosides, we have herein explored...
Carbocyclic nucleosides (-)-5'-homocarbovir and (+)-epi-4'-homocarbovir were prepared from an acylni...
The enantioselective preparation of the two isomers of 4-hydroxy-2-cyclohexanone derivatives 1a,b wa...
(D)- and (L)-cyclohexeneyl-G were synthesized enantioselectively starting from (R)-carvone. Both sho...
3,5-dihydroxy-4-(hydroxymethyl)-1-cyclohexanyl adenine has been synthesized starting from (-)-carvon...
Enantioselective synthesis of a new family of unsaturated six-membered carbocyclic nucleosides using...
A stereoselective synthesis leading to (-)-ara-cyclohexenyl-adenine is described. The synthesis star...
Cyclohexenyl nucleosides (Figure 1) represent well-known biomimetic agents, working as bioactive nuc...
A cyclohexene ring has similar structural properties and conformational behavior to a saturated five...
With the aim to expand the repertoire of these bioactive nucleosides, we are currently exploring the...
The recent advances in the chemistry of carbocyclic nucleosides focused on different synthetic appro...
Racemic metyhl 3-cyclohexene-1-carboxylate was resolved via enzymatic hydrolysis to afford the enant...
A regio- and stereo-specific synthesis of cis-(±)-3-acetoxy-5- (acetoxymethyl)cyclopentene 3 from cy...
The cyclohexane nucleosides with a 1,4-relationship between nucleoside base and hydroxymethyl moiety...
Copyright © 2018, Georg Thieme Verlag. All rights reserved. We describe a short and stereospecific s...
with the aim to expand the repertoire of bioactive cyclohexenyl nucleosides, we have herein explored...
Carbocyclic nucleosides (-)-5'-homocarbovir and (+)-epi-4'-homocarbovir were prepared from an acylni...
The enantioselective preparation of the two isomers of 4-hydroxy-2-cyclohexanone derivatives 1a,b wa...
(D)- and (L)-cyclohexeneyl-G were synthesized enantioselectively starting from (R)-carvone. Both sho...