Ambulatory arterial stiffness index: determinants and outcome

Li, Yan
Dolan, Eamon
Wang, Ji-Guang
Thijs, Lutgarde
Zhu, Ding-Liang
Staessen, Jan A
O'Brien, Eoin
Stanton, Alice

Open link

Publication date

April 2006

DOI

10.1097/01.mbp.0000189791.90488.a1

Publisher

Ovid Technologies (Wolters Kluwer Health)

Journal

Blood Pressure Monitoring

Abstract

OBJECTIVES: We hypothesized that one minus the slope of diastolic on systolic blood pressure in individual 24-h ambulatory blood pressure recordings (ambulatory arterial stiffness index) might reflect arterial stiffness and predict cardiovascular mortality. METHODS: In volunteers and a population recruited in China, we studied concordance between ambulatory arterial stiffness index and established indexes of arterial stiffness. We assessed the predictive value of ambulatory arterial stiffness index in relation to cardiovascular outcome in Irish hypertensive patients. RESULTS: In 166 healthy volunteers, aged 22-83 years, the correlation coefficient between ambulatory arterial stiffness index and pulse wave velocity was 0.51 (P<0.001). In 348...