PENGARUH RASIO OBAT DAN POLIMER TERHADAP KARAKTERISTIK MIKROSFER CIPROFLOXACIN DENGAN MATRIKS ALGINAT-KARAGENAN

alginate concentrations on the characteristic of microspheres. Ciprofloxacin HCl- alginate-carrageenan microspheres were made by ionotropic gelation method using aerosolization technique with rati of drug and polymer 1 :0.83(F1) ; 1 :1.25(F2) ; and 1 : 1 . 6 7 ( F 3 ) and CaCl 2 (0.3 M) as crosslinker. Michrospheres formed was resuspended into the solution of lyoprotectant maltodextrin and was dried using freeze dryer