Add to ORKGEpinephrine is a life-saving treatment in anaphylaxis. In community settings, a first-aid dose of epinephrine is injected from an auto-injector (EAI). Needle phobia highly contributes to EAI underuse, leading to fatalities-especially in children. A novel rapidly-disintegrating sublingual tablet (RDST) of epinephrine was developed in our laboratory as a potential alternative dosage form. The aim of this study was to evaluate the sublingual bioavailability of epinephrine 30 mg as a potential pediatric dose incorporated in our novel taste-masked RDST in comparison with intramuscular (IM) epinephrine 0.15 mg from EAI, the recommended and only available dosage form for children in community settings. We studied the rate and extent of epinephrine...
Anaphylaxis is a life-threatening condition caused by the body’s overreaction to a certain allergen....
An epinephrine (E) tablet is under development for sublingual (SL) administration for the first-aid ...
Background: Severe allergic reactions, including anaphylaxis, occur during oral food challenges (OFC...
Epinephrine is a life-saving treatment in anaphylaxis. In community settings, a first-aid dose of ep...
Epinephrine is a life-saving treatment in anaphylaxis. In community settings, a first-aid dose of ep...
Objective. to evaluate the sublingual (SL) bioavailability of E 30mg as a potential pediatric dose f...
In community settings, IM injection of 0.3 mg epinephrine (Epi) using an auto-injector is the drug o...
Objective. Our objective was to evaluate the rate and extent of absorption of epinephrine microcryst...
OBJECTIVES: For anaphylaxis treatment in community settings, adrenaline (epinephrine) administration...
BACKGROUND: Epinephrine autoinjectors are underused in the emergency treatment of anaphylaxis in the...
For the first-aid treatment of anaphylaxis, epinephrine (Epi) 0.3 mg intramuscular (IM) injection in...
Objective. To evaluate the in vitro and ex vivo diffusion of epinephrine microcrystals (Epi-MC) from...
Epinephrine is the drug of choice in the management of anaphylaxis. For first-aid treatment in the c...
Anaphylaxis is an acute and potentially lethal multisystem allergic reaction. Most consensus guideli...
auto-injectors, widely prescribed for the out-of-hospital treat-ment of anaphylaxis, have not been c...
Anaphylaxis is a life-threatening condition caused by the body’s overreaction to a certain allergen....
An epinephrine (E) tablet is under development for sublingual (SL) administration for the first-aid ...
Background: Severe allergic reactions, including anaphylaxis, occur during oral food challenges (OFC...
Epinephrine is a life-saving treatment in anaphylaxis. In community settings, a first-aid dose of ep...
Epinephrine is a life-saving treatment in anaphylaxis. In community settings, a first-aid dose of ep...
Objective. to evaluate the sublingual (SL) bioavailability of E 30mg as a potential pediatric dose f...
In community settings, IM injection of 0.3 mg epinephrine (Epi) using an auto-injector is the drug o...
Objective. Our objective was to evaluate the rate and extent of absorption of epinephrine microcryst...
OBJECTIVES: For anaphylaxis treatment in community settings, adrenaline (epinephrine) administration...
BACKGROUND: Epinephrine autoinjectors are underused in the emergency treatment of anaphylaxis in the...
For the first-aid treatment of anaphylaxis, epinephrine (Epi) 0.3 mg intramuscular (IM) injection in...
Objective. To evaluate the in vitro and ex vivo diffusion of epinephrine microcrystals (Epi-MC) from...
Epinephrine is the drug of choice in the management of anaphylaxis. For first-aid treatment in the c...
Anaphylaxis is an acute and potentially lethal multisystem allergic reaction. Most consensus guideli...
auto-injectors, widely prescribed for the out-of-hospital treat-ment of anaphylaxis, have not been c...
Anaphylaxis is a life-threatening condition caused by the body’s overreaction to a certain allergen....
An epinephrine (E) tablet is under development for sublingual (SL) administration for the first-aid ...
Background: Severe allergic reactions, including anaphylaxis, occur during oral food challenges (OFC...